A Literature Review of Artocarpus lacucha Focusing on the Phytochemical Constituents and Pharmacological Properties of the Plant

Abstract

Studies have shown that approximately two-thirds of the plant species in the world have some medicinal value. Artocarpus lakoocha is a synonym for Artocarpus lacucha and is a plant that can be found in Indonesia. This medicinal plant has been used to treat many diseases. (1) Objective: This article discusses the scientific investigations carried out on A. lacucha, namely the plant’s chemical content, pharmacological activity, and active compounds. (2) Methods: The design of this study was based on an article that was a review of previous research. A search for relevant publications over the past ten years (2012–2022) using data from Pubmed, Proquest, Ebsco, ScienceDirect, and Google Scholar resulted in the discovery of 369 articles. (3) Results: Fifty relevant articles investigate A. lacucha’s substances and their applications in the health field. The presence of secondary metabolites and bioactive compounds has been reported, which is evidence that A. lacucha possesses antidiarrheal, immunostimulant, anticholesterol, and hepatoprotective agents. (4) Conclusions: Mobe (A. lacucha) is a plant native to North Sumatra, Indonesia. This plant is efficacious as an antioxidant, antibacterial, antidiarrheal, anti-inflammatory, analgesic, antinociceptive, schistosomicidal, hepatoprotective, neuroprotective, cytotoxic, antiglycation, and anticholesterol, and can also be used for anti-aging and wound healing. In addition to its various benefits, it turns out that this plant also has many active compounds that are useful to the health sector, especially the pharmaceutical field.

Potential insecticidal extracts from Artocarpus lacucha against Spodoptera litura (Lepidoptera: Noctuidae) larvae

“…In addition to its culinary uses, monkey jack has also been used in traditional medicine for various purposes, including the treatment of asthma, anemia, dermatitis, diabetes, and diarrhea (Jagtap and Bapat 2010). Previous studies have shown that A. lacucha contains high levels of flavonoids and phenolic compounds, particularly in the ethyl acetate and methanol extracts of the leaves and bark (Duangdee et al 2019, Songoen et al 2021, Sitorus et al 2022). The bark extract has also been found to contain a number of specific compounds, including afzelechin-3-O-RL rhamnopyranoside, amyrin acetate, dihydromorin, (–)-epiafzelechin, lupeol acetate, oxyresveratrol, and catechin (Saowakon et al 2009, Islam et al 2019).…”