A Linkable, Polycarbonate Gut Microbiome‐Distal Tumor Chip Platform for Interrogating Cancer Promoting Mechanisms
Danielle S.K. Brasino,
Sean D. Speese,
Kevin Schilling
et al.
Abstract:Gut microbiome composition is tied to diseases ranging from arthritis to cancer to depression. However, mechanisms of action are poorly understood, limiting development of relevant therapeutics. Organ‐on‐chip platforms, which model minimal functional units of tissues and can tightly control communication between them, are ideal platforms to study these relationships. Many gut microbiome models are published to date but devices are typically fabricated using oxygen permeable polydimethylsiloxane, requiring inte… Show more
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