A lignan from Piper chaba stems

Bhandari, S. P. S.; Babu, Uddagiri Venkanna; Garg, H. S.

doi:10.1016/s0031-9422(97)00681-x

Cited by 17 publications

(9 citation statements)

References 11 publications

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“…In previous studies, alkaloids such as piperamine 2, 4decadienoic acid piperidide, kusunokinin and pellitorine [8], lignan [9], and a novel piperine dimer namely chabamide [10] have been isolated from the stem bark of the plant. The root has been reported to contain some alkamides such as piperine, sylvatine, piplartine and piperlonguminine besides b-sitosterol [11].…”

Section: Introductionmentioning

confidence: 99%

Antifungal Activity of Essential Oil and Extracts of Piper chaba Hunter Against Phytopathogenic Fungi

Rahman

Al-Reza²,

Kang³

2010

J Americ Oil Chem Soc

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The efficacy of the essential oil and various leaf extracts of Piper chaba Hunter was evaluated for controlling the growth of some important phytopathogenic fungi. The hydrodistilled essential oil was analysed by GC-MS. Fifty-three compounds representing 95.1% of the total oil were identified, of which a-humulene (16.4%), caryophyllene oxide (12.2%), viridiflorol (8.1%), globulol (7.4%), b-selinene (7.1%), spathulenol (6.2%), (E)-nerolidol (5.1%), linalool (4.5%) and 3-pentanol (3.5%) were the major compounds. The oil (1,000 ppm) and organic extracts (1,500 ppm) of P. chaba Hunter displayed a great potential of antifungal activity as a growth inhibition against the tested phytopathogenic fungi, Fusarium oxysporum KACC 41083, Phytophthora capsici KACC 40157, Colletotrichum capsici KACC 410978, Fusarium solani KACC 41092 and Rhizoctonia solani KACC 40111 in the range of 55.1-70.3% and minimum inhibitory concentration ranging from 125 to 500 lg/ml. The oil had also a strong detrimental effect on spore germination of all the tested fungi along with concentration as well as timedependent kinetic inhibition of P. capsici. The results obtained from this study may contribute to the development of new antifungal agents to protect crops from fungal diseases.

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Section: Introductionmentioning

confidence: 99%

Antifungal Activity of Essential Oil and Extracts of Piper chaba Hunter Against Phytopathogenic Fungi

Rahman

Al-Reza²,

Kang³

2010

J Americ Oil Chem Soc

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“…However, the configuration of this anomeric center is still unclear, as with other butyrolactol lignans (Brown and Daugan, 1989;Li et al, 2003;Gö zler et al, 1996;Bhandari et al, 1998;Rü cker and Langmann, 1978;Barrero et al, 1994;Cambie et al, 1985).…”

Section: Introductionmentioning

confidence: 99%

Configurational analysis of cubebins and bicubebin from Aristolochia lagesiana and Aristolochia pubescens

2006

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“…The qualitative and quantitative study of such bioactive compounds from plants mostly relies on the selection of proper extraction method [30,31]. Piper chaba has been traditionally used as a source of natural therapeutics [32]. In this paper we have isolated and purified four different compounds (about 20% to 22% dry weight; up to 99.9% purity) from the stem of Piper chaba by development of unique methods of both convention and non-conventional processes with high …”

Section: Discussionmentioning

confidence: 99%

Optimized Analytical Techniques for Extraction and Separation of Bioactive Compounds from Diverse Plant Types

Biswas¹

2017

Biochem Anal Biochem

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Bioactive compounds (BACs) from plants provide unlimited opportunities for pharmaceuticals and natural agrochemicals development due to vast diversity of secondary compounds. Successful identification and development of natural products from plants necessitates a standard and integrated approach to screen compounds which aids in determination of dose response activity. We examined Peperomia pellucida (herb with fibrous root), Cleome viscosa (herb with tap root), Piper chaba (climber) and Artocarpus lakoocha (tree). In C. viscosa plants, BACs were collected from 'Root Exudates Trapping System' made of Buchner funnel and conical flask, while compounds were collected from P. pellucida by a self-designed horizontal tube like glass ware with stopper and funnel at either end. BACs are extracted from stem and leaves dust of P. chaba and A. lakoocha respectively. The basic sequential steps are same included grinding of plant parts, homogenization, vacuum filtration followed by liquid-liquid extraction in which BACs were fractionated into two major phases (ethyl acetate layer and aqueous layer). The extracts were further purified into a single pure compound by repetitive running through column and subsequently followed by thin layer chromatography and finally subjected to spectral analyses (viz. MS, IR, 1 HNMR and 13 CNMR) for complete molecular characterization. A new Phenol glycoside was isolated from Peperomia pellucida and Lactam nonanoic acid was recovered from Cleome viscosa. Four major compounds were recovered from Piper chaba and Artocarpus lakoocha with remarkable bioactivity but only the important fractions are described here. These new extraction techniques will extend and enhance the usefulness of plants as renewable resources of valuable chemicals.

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A lignan from Piper chaba stems

Cited by 17 publications

References 11 publications

Antifungal Activity of Essential Oil and Extracts of Piper chaba Hunter Against Phytopathogenic Fungi

Antifungal Activity of Essential Oil and Extracts of Piper chaba Hunter Against Phytopathogenic Fungi

Configurational analysis of cubebins and bicubebin from Aristolochia lagesiana and Aristolochia pubescens

Optimized Analytical Techniques for Extraction and Separation of Bioactive Compounds from Diverse Plant Types

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