A light-gated regulation of the reaction site by a cucurbit[7]uril macrocycle

Abstract

Competitive inhibition can be overcome by increasing the amount of catalyst in the reaction mixture. Here we present a pseudorotaxane system that circumvents this rule. A merocyanine inhibitor linked with...

The Diversity of Cucurbituril Molecular Switches and Shuttles

“…Finally, Sashuk and coworkers reported a CB [7] complex where the host sited preferentially on a heptane spacer, separating a merocyanine and a dimethylammonium-benzaldehyde group. [55] Its UV light irradiation induced conversion of the merocyanine into a spiropyran and forced CB [7] to occupy the dimethylammonium-benzaldehyde position, which enhanced the benzaldehyde reactivity and selectivity toward various hydrazides. This original light activated SMS system allows the control of the CB [7] catalytic activity.…”

Photoswitchable catalysis by a self-assembled molecular cage

“…46 In these examples, the catalysis is switched by changing the electronic properties of a donor atom, 47 blocking an active site with steric bulk, 42 bringing together cooperative organocatalytic groups, 43 or forming a more reactive functional group. 48 While there are reports of switchable catalysis within macrocycles, [49][50] on surfaces of nanoparticles, 51-54 and using rotaxanes, 55 to the best of our knowledge, there are no reports of photoswitchable catalysis using discrete self-assembled species. Herein we report light-regulated catalysis using a heteroleptic [Pd2L2L'2] 4+ cage system (Figure 1).…”

Photoswitchable catalysis by a self-assembled molecular cage

“…46 In these examples, the catalysis is switched by changing the electronic properties of a donor atom, 47 blocking an active site with steric bulk, 42 bringing together cooperative organocatalytic groups, 43 or forming a more reactive functional group. 48 While there are reports of switchable catalysis within macrocycles, [49][50] on surfaces of nanoparticles, 51-54 and using rotaxanes, 55 to the best of our knowledge, there are no reports of photoswitchable catalysis using discrete self-assembled species. Herein we report lightregulated catalysis using a heteroleptic [Pd2L2L'2] 4+ cage system (Figure 1).…”