A lesion of the patella: An unexpected location of Rosai-Dorfman disease: A case report

Sassi, Farah; M'rad, Haythem; Kacem, Linda Belhaj; Sassi, Boubaker; Hannachi, Samia; Rammeh, Soumaya

doi:10.1016/j.ijscr.2022.107510

Cited by 1 publication

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The number of lymph nodes involved varied among the patients. Multiple lymph nodes were found in a total of 4 studies, involving 6 39 , 4 34 , 3 52 and 2 54 nodal sites while 7 studies 34,40,45,46,50,51,56 reported only one lymph node involvement. The types of lymph nodes affected (Fig.…”

Section: Resultsmentioning

confidence: 99%

Manifestations, Diagnosis and Treatment of Osseous Rosai-Dorfman Disease: A Systematic Review

Agarwal,

Abozeed

2023

Preprint

View full text Add to dashboard Cite

BACKGROUND We hypothesize that lymphadenopathy and extraosseous manifestation affect the management protocol and our aim is to aid in development of standardized diagnosis and treatment protocols. METHODS PubMed and Google Scholar were searched from January 2012 through December 2022 using keywords Rosai-Dorfman, Rosai and Dorfman, and bone. Out of 98 researches, meta-analysis of 51 full-text studies involving 53 individuals with osseous RDD was conducted. RESULTS A significant association was found between lymphadenopathy with steroid therapy (OR: 20.125, 95%CI: 3.02, 134.09, P=0.0004). Extraosseous RDD showed significant association with steroid therapy (P=0.0145), T1-isointense MRI (OR: 0.173, 95%CI: 0.0304, 0.986, P=0.035), T1-hyperintense MRI (OR: 0.16, 95%CI: 0.0314, 0.815, P=0.019) and T2-hyperintense MRI (OR: 0.115, 95%CI= 0.0206, 0.6456, P=0.007). CONCLUSION Osseous RDD is rare and lacks standardized diagnosis and treatment protocols. Patients with lymphadenopathy were 9 times more likely to receive steroids, and those with extraosseous manifestations were less likely to undergo MRI. RDD is often not initially considered in differential diagnoses, leading to worsened conditions. We propose that further testing is required in affected individuals to develop standardized protocols.

show abstract