A large sinonasal schwannoma: a rare entity

Abstract

<p class="keywords"><span lang="EN-IN">Schwannoma is a rare neoplasm of nose and PNS which develops from Schwann’s cells of neural sheath and most are benign and encapsulated and amenable to surgical excision. The aim of this write-up is to report a rare case of schwannoma of nose and PNS. We report a case of 40 year old female, a housewife, presented in ENT OPD with complaints of nasal obstruction on right side, post nasal drip and headache. On diagnostic nasal endoscopy, there was a polypoidal mass coming from the middle meatus which was pushing the medial turbinate medially. NCCT and MRI of nose and PNS showed soft tissue density mass involving right ethmoidal air cells, maxillary sinus and bilateral sphenoid sinuses and eroding the lateral wall of right maxillary sinus reaching upto infratemporal fossa, superiorly mass was seen eroding the inferior wall of right orbit. The tumour was removed endoscopically piecemeal and sent for histopathology which showed it to be a schwannoma. The conclusion of the finding was schwannoma involving nasal cavity, maxillary sinus and sphenoid sinus eroded the lateral wall of maxillary sinus going into infratemporal fossa and floor of the orbit. Schwannoma should also be kept as a possibility in the differential diagnosis of tumors of nose and PNS. </span></p>

Schwannoma nasal cavity: a clinicopathological case report

“…Schwannomas are benign nerve sheath tumors arising from the Schwann cells in the peripheral nerve sheath that are derived from the neuroectoderm, first described by Verocay in 1908. In the year 1935, Stout coined the term Neurilemmoma believing that this tumor arose from cells of sheath of Schwann 5 . Since these tumors are schwannian in origin, it is suggested that the term schwannoma be used more freuquently.…”

Right Ethmoidal Sinus Schwannoma: Case Report of a Common Entity with an Unusual Presentation

“…Mitra B et al [2] , Vaidya MM et al [3] , Dhawle MS et al [4] and Mangubat EZ et al [6] documented schwannoma in male patient. On the contrary, Singh M et al [5] , Mosalleum EMA [7] and Wong E et al [8] reported the lesion in female patients in their case reports.…”

“…Vaidya MM et al [3] , Dhawle MS et al [4] , Mangubat EZ et al [6] , Mosalleum EMA [7] et al documented the tumor in fourth decade. Singh M et al [5] observed the lesion in fifth decade.…”

“…Schwannomas are benign slow growing nerve sheath tumors that arise from schwann cells, derived from the neuroectoderm. [4,5] Solitary schwannoma is also called as neurilemmoma, neurolemmoma, perineural fibroblastoma and neurinoma. [2,5] Schwannommas may be encountered at any age.…”

“…Dhawle MS et al [4] documented the tumor arising from right maxillary sinus. Singh M et al [5] reported the lesion involving the right ethmoidal sinus, maxillary sinus and bilateral sphenoidal sinuses. Mangubat EZ et al [6] described a case of schwannoma presenting as right frontal sinus lesion.…”