A laboratory method for the single‐passage selection of drug‐resistant mutants from populations ofEimeriaspecies in chickens and its potential value in the choice of field use concentrations for new anticoccidial drugs
Abstract:Populations of Eimeria species in chickens frequently include mutants that are resistant to an anticoccidial drug without having been previously exposed to it. Such mutants are described here as 'inherently resistant'. A novel laboratory method of selecting them from their parent populations is described. Selection may be achieved in a single in vivo passage in chickens. Decoquinate-resistant mutants were selected from a previously unexposed E. tenella strain: they tolerated > 0.625% w/w decoquinate in the foo… Show more
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