“…Specifically, the medical expert system could perform a complicated and vigorous task using knowledge based that would be carried out by a human expert in diagnosis or treatment of a disease and many other prototypes were implemented to solve medical problems in respiratory system, namely a management of weaning (Hernández-Sande et al, 1989), a control of general anesthesia (Greenhow et al, 1993), a diagnosis and therapy in lung transplantation (Prasad et al, 1996), asthma care (Shegog et al, 2004), a diagnosis of pulmonary embolism (Serpen et al, 2008) and a diagnosis of lung cancer (Avci, 2012). To our knowledge in the context of a closed-loop expert system for mechanical ventilation, the first application was for weaning in order to withdraw the patient from the ventilator (Hernández-Sande et al, 1989;Dojat et al, 1992).…”