A Khorasan wheat‐based diet improves systemic inflammatory profile in semi‐professional basketball players: a randomized crossover pilot study

Abstract

BACKGROUND/OBJECTIVESKhorasan wheat is an ancient grain with widely acclaimed beneficial effects on human health. The objective of the study was to examine the effect of a Khorasan‐based diet on the wellbeing and inflammatory profile of young athletes.RESULTSWe conducted a randomized, single‐blinded crossover trial involving 20 male young athletes. The participants were randomly assigned to consume products (pasta, bread, biscuits and crackers) made either with Khorasan (KAMUT® brand) or modern semi‐whole‐grain wheat for 4‐weeks with a 4‐week washout period before the crossover. Laboratory analyses and fitness tests were performed both at the beginning and end of each diet period. The consumption of Khorasan products was associated with a significant reduction of monocyte chemoattractant protein‐1 (MCP‐1; mean reduction: −36.15 pg/mL; −25.67%) while the consumption of modern wheat was not associated with significant differences in Interleukin‐8 (IL‐8) or Interleukin‐1 receptor antagonist (IL‐1ra). The consumption of the Khorasan‐based diet also resulted in a significant improvement in self‐rated health status. No statistically significant differences in any athletic performance parameter were observed between the two diets.CONCLUSIONThe present results suggest that a Khorasan‐based diet could be effective in reducing the inflammatory status in young athletes. © 2019 Society of Chemical Industry

Differential Physiological Responses Elicited by Ancient and Heritage Wheat Cultivars Compared to Modern Ones

“…From an inflammatory point of view, however, significant decreases were observed in some pro-inflammatory circulating cytokines, such as IL-1ra, IL-8, and Tumor necrosis factor alpha (TNF-α), in NAFLD patients after the dietary intervention with the Khorasan heritage wheat [82]. A systemic anti-inflammatory effect of Khorasan wheat consumption was also detected by our group in a recent randomized crossover pilot study involving 20 professional or semi-professional athletes [7]. In our study, after four weeks of a Khorasan-based diet, a significant reduction in blood levels of the Monocyte chemoattractant protein 1 (MCP-1), a pro-inflammatory chemokine produced by muscle during strenuous activity, was recorded.…”

“…The wheat cultivars introduced during the last centuries before the second World War are, therefore, defined as heritage varieties, thus diversifying them from the ancient cultivars that date back to the previous millennia. In addition, heritage varieties usually have higher protein content respect to modern ones [7]. Flour quality, gluten strength (W), obtainable products, and protein content according to the parameters conventionally required by the food industry.…”

Effects of White Pan Bread Added with Kamut (Triticum turgidum spp.) on High Fat Diet-Induced Obese C57BL/6 Mice

“…카무트는 필수아미노산, 무기질 및 비타민을 풍부하 게 함유하고 있을 뿐만 아니라 식이섬유소, 셀레늄, 폴리 페놀 등의 다양한 생리활성 성분 함유량이 일반 밀에 비 해 높은 것으로 알려져 있다 6,7) . 카무트는 체 내 면역기능 개선 효능, 혈관건강 개선 효능, 항산화 활성, 항당뇨 효 과 등 다양한 생리활성이 보고되었으며, 특히 카무트 식 단을 섭취한 사람들은 혈중 지질 개선 및 염증반응 억제 효능을 나타내어 심혈관 질환 발병 위험이 감소하는 것으 로 보고되었다 [7][8][9][10][11] . 뿐만 아니라 카무트를 첨가하여 제조 한 쿠키, 빵, 파스타 등의 곡류 제품은 다른 밀을 이용하 여 만든 제품에 비해 혈중 항산화 효소 활성 증가, 간 및 소장 내 염증 개선 효능 등이 보고된 바 있다 [12][13][14] .…”