A joint strategy comprising melatonin and 3-methyladenine to concurrently stimulate biomass and astaxanthin hyperaccumulation by Haematococcus pluvialis

Zhao, Yongteng; Cui, Jing; Li, Qingqing; Qiao, Tengsheng; Zhong, Du-bo; Zhao, Peng; Yu, Xuya

doi:10.1016/j.biortech.2021.125784

Cited by 19 publications

(2 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, it was selected as an amino acid metabolism inhibitory additive. In addition, melatonin was selected as a lipid pathway promoter because of its ability to enhance lipid production (Zhao et al, 2021). lipid metabolism.…”

Section: Regulation Of Amino Acid and Lipid Metabolism By Metabolic R...mentioning

confidence: 99%

Metabolomics of astaxanthin biosynthesis and corresponding regulation strategies in Phaffia rhodozyma

Yang

et al. 2023

Yeast

View full text Add to dashboard Cite

Astaxanthin is a valuable carotenoid and is used as antioxidant and health care. Phaffia rhodozyma is a potential strain for the biosynthesis of astaxanthin. The unclear metabolic characteristics of P. rhodozyma at different metabolic stages hinder astaxanthin's promotion. This study is conducted to investigate metabolite changes based on quadrupole time‐of‐flight mass spectrometry metabolomics method. The results showed that the downregulation of purine, pyrimidine, amino acid synthesis, and glycolytic pathways contributed to astaxanthin biosynthesis. Meanwhile, the upregulation of lipid metabolites contributed to astaxanthin accumulation. Therefore, the regulation strategies were proposed based on this. The addition of sodium orthovanadate inhibited the amino acid pathway to increase astaxanthin concentration by 19.2%. And the addition of melatonin promoted lipid metabolism to increase the astaxanthin concentration by 30.3%. It further confirmed that inhibition of amino acid metabolism and promotion of lipid metabolism were beneficial for astaxanthin biosynthesis of P. rhodozyma. It is helpful in understanding metabolic pathways affecting astaxanthin of P. rhodozyma and provides regulatory strategies for metabolism.

show abstract

Section: Regulation Of Amino Acid and Lipid Metabolism By Metabolic R...mentioning

confidence: 99%

Metabolomics of astaxanthin biosynthesis and corresponding regulation strategies in Phaffia rhodozyma

Yang

et al. 2023

Yeast

View full text Add to dashboard Cite

show abstract

“…The concentration of 500 µM melatonin showed the lowest biomass productivity at all wavelengths compared to other dosages. Previous studies investigated that biomass reduction is probably due to the stressful effects of melatonin in high concentrations(Li et al 2017, Zhao et al 2021a…”

mentioning

confidence: 99%

The novel strategy for enhancing growth and lipid accumulation in C.vulgaris microalgae cultured in dairy wastewater by monochromatic LEDs and melatonin

Samani

Mansouri

2022

Preprint

View full text Add to dashboard Cite

The present study investigated the effects of melatonin hormone and monochromatic light-emitting diodes (LEDs) on the biomass productivity and lipid accumulation of C.vulgaris green microalgae. Four monochromatic LEDs were applied individually or simultaneously with melatonin in dairy wastewater. For reducing the cultivation costs dairy wastewater is utilized for the culture medium. In free melatonin samples, the maximum biomass productivity was observed under red, blue, green and white LEDs. The biomolecules including protein, carbohydrate, lipid and pigment increased by monochromatic LEDs application compared to white LEDs. Melatonin application in culture medium increased parameters compared to free melatonin samples. The simultaneous treatment of red LED with concentration of 10 µM melatonin increased the biomass productivity and biomolecules by approximately 200% compared to control samples. In addition, the fatty acid profile improved under simultaneous treatment. The MUFAs and PUFAs increased by 22% and 8% compared to control. The SFAs decreased from 85.58% in control samples to 56.93 under red wavelength and melatonin hormone. These findings demonstrated that the monochromatic LEDs application and exogenous melatonin is the novel economical treatments for C.vulgaris microalgae cultivation, which increase biomass production and biomolecules accumulation.

show abstract

Potential, Mechanism and Molecular Insight of Melatonin in Phyto-Remediation

Riaz,

Shahzad,

Shafiq

et al. 2023

Plant in Challenging Environments

View full text Add to dashboard Cite

A joint strategy comprising melatonin and 3-methyladenine to concurrently stimulate biomass and astaxanthin hyperaccumulation by Haematococcus pluvialis

Cited by 19 publications

References 38 publications

Metabolomics of astaxanthin biosynthesis and corresponding regulation strategies in Phaffia rhodozyma

Metabolomics of astaxanthin biosynthesis and corresponding regulation strategies in Phaffia rhodozyma

The novel strategy for enhancing growth and lipid accumulation in C.vulgaris microalgae cultured in dairy wastewater by monochromatic LEDs and melatonin

Potential, Mechanism and Molecular Insight of Melatonin in Phyto-Remediation

Contact Info

Product

Resources

About