A Jehovah’s Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery

Posterior vertebral column resection in a 10‐year‐old boy with haemophilia B and congenital kyphosis – a case report and literature review

“…Patients with haemophilia B could receive surgeries under proper replacement therapy with recombinant factor IX concentrate, PPCs or blood coagulation factor VII (rFVIIa) [1,2]. Haemophilia B (Christmas disease) is characterized by an inherited deficiency of factor IX (FIX).…”

“…Patients with haemophilia B could receive surgeries under proper replacement therapy with recombinant FIX concentrate, PPCs or blood coagulation factor VII (rFVIIa) [1,2]. Chan et al [1] reported their experiences of perioperative treatment of a child with haemophilia B and FIX inhibitors with activated recombinant human blood coagulation factor VII (rFVIIa) undergoing surgery of idiopathic scoliosis.…”

“…In patients with target joints, acute synovitis due to recurrent bleeding progresses over time to chronic synovitis, ultimately leading to cartilage and bone destruction known as haemarthropathy [1,2]. However, the surgeon should pay attention to the complications due to the haemorrhagic disorder.…”