Abstract:Background. Muscle mass plays a key role in recovery from critical illness or severe trauma. Low skeletal muscle mass is associated with increased mortality risk in patients with coronary heart disease (Nichols et al., 2019). Sarcopenia, low muscle mass, is an increasing problem in our ageing society. The prevalence of sarcopenia varies extremely between elderly cohorts ranging from 7 to over 50% (Bijlsma et al., 2013). Due to their phylogenetic relatedness mice have long served as models of human biology incl… Show more
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