2016
DOI: 10.1155/2016/7312472
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A Fomitopsis pinicola Jeseng Formulation Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High‐Fat Diet‐Induced Obesity

Abstract: This study investigated the antiobesity effect of an extract of the Fomitopsis pinicola Jeseng-containing formulation (FAVA), which is a combination of four natural components: Fomitopsis pinicola Jeseng; Acanthopanax senticosus; Viscum album coloratum; and Allium tuberosum. High-fat diet- (HFD-) fed male C57BL/6J mice were treated with FAVA (200 mg/kg/day) for 12 weeks to monitor the antiobesity effect and amelioration of nonalcoholic fatty liver diseases (NAFLD). Body and white adipose tissue (WAT) weights w… Show more

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Cited by 9 publications
(8 citation statements)
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References 43 publications
(40 reference statements)
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“…7B, suggested that EMO could decrease lipogenesis by a pathway that SREBP-1c down-regulated the expression of FAS and PPARγ, and the similar result was observed that SREBP-1cregulated the mRNA levels of PPARγ and FAS 15 . In addition to, PPARγ also be able to induce the C/EBP-α which is a transcription factor can directly control adipocyte differentiation 14 , while it needs to be further confirmed whether EMO could improve NAFLD via this mechanism. In contrast, the expressions of the genes related with β-oxidation of fatty acid were also analyzed.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…7B, suggested that EMO could decrease lipogenesis by a pathway that SREBP-1c down-regulated the expression of FAS and PPARγ, and the similar result was observed that SREBP-1cregulated the mRNA levels of PPARγ and FAS 15 . In addition to, PPARγ also be able to induce the C/EBP-α which is a transcription factor can directly control adipocyte differentiation 14 , while it needs to be further confirmed whether EMO could improve NAFLD via this mechanism. In contrast, the expressions of the genes related with β-oxidation of fatty acid were also analyzed.…”
Section: Discussionmentioning
confidence: 99%
“…It is generally known that long-term high-fat diet consumption directly induced obesity, which accompanied with NAFLD 14,40 . NAFLD is a pervasive chronic disease and is characterized to hepatic lipids accumulation and lipids metabolic disorders 11 .…”
Section: Discussionmentioning
confidence: 99%
“…So FAVA efficient remedy for reversing fat body and fatty liver because of excessive fats intake. (Jung et al, 2016) 3.4 Anti-inflammatory effect: 3.4.1 Anti-angiogenesis and anti-inflammatory effect of F.pinicola: In the new age, health foods more frequently used because of maintaining good health. More specifically, mushroom's diets are consumed greatly, believed to have anti-tumor effects with low hazard to internal tissues.…”
Section: Effect On Glucose and Lipid Metabolismmentioning
confidence: 99%
“…M: tónico general, antiséptico, carminativo, digestivo, emético, protector renal y estomacal, cordial, depurativo. E: hepatoprotector, antiobesidad (Jung et al 2016), antioxidante, antimicrobiano (Mnayer et al 2014), antifúngico (Kocevski et al 2013), anticáncer, citotóxico , afrodisíaco (Sahoo et al 2014); insecticida (Shi et al 2015). E: anti-dispepsia, digestivo, antidiarreico, antimalárico (Hempen & Fischer 2009), antiinflamatorio , antimicrobiano (Moon et al 2004;Yang et al 2008;Dai et al 2015), anti-VIH (Kobayashi et al 2000), antioxidante, hipoglucémico, hipolipidémico (Yu & Suzuki 2007;Yu et al 2008), anticoagulante (Jeon et al 2008), anticáncer (Yang et al 2009(Yang et al , 2010, neuroprotector , sedante, hipnótico (Feng et al 2009).…”
Section: Amaryllidaceae Asia Cálida Jiu Puerro Chino Partes Aéreas Funclassified
“…Fabaceae Siberia, Mongolia, Afganistán, Kazakstán, Kirguistán, Tayikistán, Pakistán, China Gan cao Raíces secas fragmentadas envasadas [B040] M: antitusivo, antiasmático, trastornos pulmonares, bronquial, dolor de garganta, antiinfamatorio, hepático, anticonvulsivo, trastornos gastrointestinales, antiulcerogénico, anti-ántrax, antidermatósico, afrodisíaco anti-histeria, anti-fatiga, antiestrés. E: antitusivo, antiasmático, antioxidante, antiinflamatorio, antirreumático, antitrombótico, antialérgico, hepatoprotector, anti-arterioesclerosis, antimicrobiano, antiviral, antimalárico, antiulcerogénico, antiespasmódico, antiácido, anticáncer (Foster & Yue 1992;Tang & Eisenbrand 2013;Ji et al 2016), cardioprotector , progestogénico, antiprogestogénico (Ahmed et al 2014), antisifilítico (Drobnik 2016), desintoxicante (Peter et al 2013), inmunomodulador (Ayeka et al 2016), antiemético, gastroprotector , antidermatósico (Cha et al 2016), neuroprotector (Link et al 2015;Zarmouh et al 2016), antidepresivo (Rajput et al 2011), potenciador del deseo sexual (Yarnell & Abascal 2013), adaptógeno (Shang et al 2009;Corneanu & Corneanu 2013). Houttuynia cordata Thunb.…”
Section: Colocasia Esculenta (L) Schott Araceae China Taiwán Yu Tarunclassified