Smart distribution network will achieve the optimal operation of the distribution network, provide high-quality and reliable power, guarantee the development of modern social economy. The deep integration of cyber system and power physical system is the key to smart distribution network. The emergence of cyber-physical system (CPS) provides a new way to solve this problem, the cyber-physical model for smart distribution grid becomes an urgent problem to be solved. In this paper, the content and method of cyber-physical model for smart distribution grid are analyzed by combining with the coupling of information flow and power flow of smart distribution network from the perspective of cyber-physical model. At last, taking 110 kV typical substation as an example, the coupling mechanism and function of power flow and information flow is studied.