The microstructure and local mechanical properties of zones of 12Cr18Ni10Ti steel and a titanium alloy VT1-0 with an intermediate copper insert joint were carried out. The study was performed using electronic scanning microscopy, microindentation and scratch tests. The phase composition was determined by the EBSD analysis. Dissolution and mixing of welded materials in a copper are observed. The material of joint is a supersaturated solid solution of Fe, Ni, Cr, Ti in the copper crystal lattice with uniformly distributed particles of TiFe, Ti(Fe,Cr) 2 , and CuTi 2. A diffusion zones with a changed chemical composition 10 ÷ 150 μm thick and a microhardness of 2,9 ÷ 3,4 GPa are formed on the boundary with steel, and at a boundary with a titanium alloy-50 ÷ 100 μm thick and the microhardness of 4,6 ÷ 6 GPa. The microhardness of steel is 2,7 ÷ 3,1 GPa, titanium alloy-2,4 ÷ 2,8 GPa, solid solution based on copper-1,7 ÷ 2,1 GPa, intermetallides-3,8 ÷ 4,9 GPa. The stress-strain diagrams for zones of the joint are received using the original technique for determining coefficients of the "stress-strain" diagram by microindentation and scratch tests. The diffusion zone on the boundary with titanium is greater strength. There is established the formation of a solid solution based on β-titanium and dispersed particles of CuTi 2 and then-intermetallides of Ti(Fe,Cr) 2. The obtained data can be used to estimate stress-strain state, strength and efficiency of the joint under load and to give recommendations for practical.