A hyaluronic acid dispersed carbon nanotube electrode used for a mediatorless NADH sensing and biosensing

Filip, Jaroslav; Šefčovičová, Jana; Tomčı́k, Peter; Gemeiner, Peter; Tkáč, Ján

doi:10.1016/j.talanta.2011.01.004

Cited by 52 publications

(31 citation statements)

References 59 publications

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“…A composite based on CNTs, chitosan and dopamine allowed a very sensitive detection of NADH with no interference by AA and uric acid [7]. A nanocomposite consisting of single-walled carbon nanotubes dispersed in a hyaluronic acid was investigated as a biocompatible sensing platform for electrochemical detection of NADH [8]. Graphene presents excellent electrical conductivity, mainly due to the delocalized π bonds above and below the basal plane, a large surface area and lately become an interesting alternative for developing electrochemical sensors.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical determination of NADH using screen printed carbon electrodes modified with reduced graphene oxide and poly(allylamine hydrochloride)

2015

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We describe a new type of NADH sensor based on a screen-printed electrode (SPE) modified with reduced graphene oxide (RGO) and poly(allylamine hydrochloride) (PAH). A mixture of graphene oxide (GO) and PAH was deposited on the surface of a carbon working electrode, and RGO was prepared in-situ by electrochemical reduction of GO. The oxidation peak of NADH was recorded at +450 mV (vs. silver pseudo-reference). Under optimized conditions, the electrode exhibits high electrocatalytic activity toward NADH oxidation, expressed by a high rate constant and a stable response up to 0.8 mM concentrations. The sensitivity is 108.6 μA·mM −1 ·cm −2 , the response time is 20 s (for 95 % of the steady state current), and the detection limit is 6.6 μM (at an S/N ratio of 3). A peak separation of about 300 mV was achieved in differential pulse voltammetric determination of NADH in the presence of ascorbic acid. This makes the new sensor a useful tool with potential analytical application in different dehydrogenase based systems.

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Section: Introductionmentioning

confidence: 99%

Electrochemical determination of NADH using screen printed carbon electrodes modified with reduced graphene oxide and poly(allylamine hydrochloride)

2015

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“…The most significant characteristic is a very wide linear range (59-5800 μM, r = 0.998) compared with the other NADH sensors based on SWCNTs, as shown in Table 1. (10)(11)(12)(15)(16)(17)21,30,31) At high concentrations (>3 mM), no current saturation was observed, unlike in conventional NADH sensors. This is attributed to the effective electrochemical communication provided by the electronically homogeneous s-SWCNTs.…”

Section: Nadh Sensingmentioning

confidence: 95%

“…Therefore, the use of mediatorless sensors has also been reported as the second approach. (11,17,30) The main issues with this approach are the use of a functional (inactive) matrix, such as hyaluronic acid, (11) PPF, (30) or polyaniline. (17) There have been other attempts to use carbon nanotubes that have been subjected to boron doping, (31) nitrogen doping, (32) boiling in water, (24) and acid microwave treatment; (24) however, these approaches are only available for multiwalled carbon nanotubes.…”

Section: Nadh Sensingmentioning

confidence: 99%

“…Recently, there has been an increase in the number of reports of NADH sensing with SWCNTs because of their excellent electron transfer properties and catalytic activities. (10)(11)(12)(13)(14)(15)(16)(17)(18) In this article, the effect of electronically type-sorted SWCNTs on electrochemical performance is addressed and their analytical applications are examined. The investigation of the effectiveness of electrochemical sensors with electronically type-sorted SWCNTs is a challenging task because these chemical sensors work in aqueous media, unlike other electronic (3)(4)(5) and electrochemical (7) devices that work in the atmosphere.…”

Section: Introductionmentioning

confidence: 99%

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Electrochemical Behavior and Analytical Applications of Electronically Type-Sorted Carbon Nanotube Electrode

2016

Sensors and Materials

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Keywords: electronically type-sorted single-walled carbon nanotube, plasma-polymerized film, electrochemical sensor, nicotinamide adenine dinucleotideThe electrochemical behavior and analytical applications of an electrode with electronically typesorted (metallic and semiconducting) single-walled carbon nanotubes (SWCNTs) were examined. The effect of the electronic type of SWCNTs on the electrochemical behavior of nicotinamide adenine dinucleotide (NADH) as a model agent was investigated. The electrode configuration contained SWCNTs sandwiched between 3-5-nm-thick acetonitrile plasma-polymerized thin films. Cyclic voltammetry measurements demonstrated that the current due to the NADH oxidation of the electrode with semiconducting SWCNTs was much larger than that for electrodes with only metallic or unsorted SWCNTs. Electrochemical impedance spectroscopy measurements and atomic force microscopy observations suggested that the electrode with semiconducting SWCNTs formed a better electron transfer network than the electrodes with metallic or unsorted SWCNTs. Chronocoulometry measurements indicated that there was no distinct difference between the diffusion coefficients of NADH with the metallic and semiconducting SWCNT electrodes. Therefore, it was concluded that the semiconducting SWCNT electrode is more suitable than the metallic and unsorted SWCNT electrodes for electrochemical oxidation in terms of catalysis and electron transport. The semiconducting SWCNT electrode exhibited excellent performance for the sensing application of NADH detection with a significantly wide linear range of 59-5800 μM compared with that for conventional NADH sensors. Other significant performance characteristics are a sensitivity of 176 μA mM −1 cm −2 (defined as the slope of the current vs concentration plot at +0.4 V), a detection limit of 1.1 μM [signal-to-noise ratio (S/N) = 3], and a response time of 6 s.

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“…Recently, there has been an increase in the number of reports of electrochemical determination of NADH with carbon nanotube (CNT) electrodes because of their excellent electron transfer properties and catalytic activities. [1][2][3][4][5][6][7][8][9] One problem is that the oxidative potential of NADH is larger than that of AA and UA. Utilization of electron transfer mediators [4][5][6][7][8][9] and functional materials 1-3 is mostly used strategy.…”

Section: Introductionmentioning

confidence: 99%

Selective Determination of Nicotinamide Adenine Dinucleotide in the Presence of Ascorbic Acid and Uric Acid at a Long-Length Carbon Nanotube Electrode

Hikichi

Muguruma

Inoue³

et al. 2017

Electrochemistry

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Selective electrochemical determination of nicotinamide adenine dinucleotide (NADH) in the presence of ascorbic acid (AA) and uric acid (UA) at a long-length multi-walled carbon nanotube (CNT) electrode is presented. We demonstrate the effectiveness of CNT length toward the electrochemical response due to oxidation of NADH. The long-length CNT is 200 µm (average), whereas normal-length CNT as a comparison is 1 µm (average). In differential pulse voltammetry, the current peaks due to NADH, AA, and UA at long-length CNT electrodes were more distinct than those at normal-length electrode. Electrochemical impedance spectroscopy measurements suggested that the long-length CNT electrode formed a better electron transfer network than the normal-length electrode. The performance of selective determination of NADH are concentration range of 0.030-2.0 mM in the presence of 1.2 mM AA, and 0.059-2.0 mM in the presence of 0.12 mM UA.

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A hyaluronic acid dispersed carbon nanotube electrode used for a mediatorless NADH sensing and biosensing

Cited by 52 publications

References 59 publications

Electrochemical determination of NADH using screen printed carbon electrodes modified with reduced graphene oxide and poly(allylamine hydrochloride)

Electrochemical determination of NADH using screen printed carbon electrodes modified with reduced graphene oxide and poly(allylamine hydrochloride)

Electrochemical Behavior and Analytical Applications of Electronically Type-Sorted Carbon Nanotube Electrode

Selective Determination of Nicotinamide Adenine Dinucleotide in the Presence of Ascorbic Acid and Uric Acid at a Long-Length Carbon Nanotube Electrode

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