“…the interactions) if the input PPIs are described by standard UniProt ID or yeast SGD IDs. For user convenience, the proposed approach includes other conventionally adopted network clustering methods (e.g., CPM (Palla et al, 2005), FastGreedy (Clauset et al, 2004), HUNTER (Chin et al, 2010), LE (Newman, 2006), MCL (van Dongen, 2000), SpinGlass (Reichardt and Bornholdt, 2006), and WalkTrap (Pons and Latapy, 2005)) in Spotlight platform to easily perform network analysis, as well as view/export, and link results to further functional analysis processes. The Spotlight-based integrating graph clustering method outperforms other network clustering methods by exploiting unique network properties that imply the functional association among proteins.…”