Abstract:The host recognition modules encoding the injection machinery and receptor binding proteins (RBPs) of bacteriophages are variable genomic units predisposed to mutation and recombination to maintain infectivity toward co-evolving bacterial hosts. In this study, we reveal how Alteromonas mediterranea schitovirus A5 shares its host recognition module, including tail fiber (TF) and cognate chaperone, with phages from distantly related families including Alteromonas myovirus, V22. While the chaperone of V22 is esse… Show more
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