A homogeneous high-throughput array for the detection and discrimination of influenza A viruses

Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues

“…This research offers insights into the construction of imaging probes that can target pathogen-conserved metabolic pathways, making possible the development of simple and clinically transformable fluorescent agents and materials for the timely monitoring of bacterial infections in situ . The development of fluorescent probes that can be activated by species-specific biomarkers in order to further enhance imaging precision is underway in our group. − Moreover, owing to the inherent antimicrobial properties of GO, we are also exploring the use of PABA-DCM@GO hydrogel dressing for image-guided photodynamic and/or photothermal therapy of bacterial infections. − …”

Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy

“…Among all types of FI and PDT-active agents, organic dyes are advantageous in terms of the readily tunable photophysical properties using simple structural modifications. 12–18 However, most of the reported organic dyes suffer from aggregation-caused quenching (ACQ) in both fluorescence and singlet-oxygen yield, and non-selective localization in cells. Aggregation-induced emission (AIE) was first reported by the Tang group, 19 and describes the enhanced fluorescence of organic dyes in their aggregated states.…”

From poly(vinylimidazole) to cationic glycopolymers and glyco-particles: effective antibacterial agents with enhanced biocompatibility and selectivity

“…Cationic glycopolymers are usually prepared by copolymerization of a neutral glycomonomer with a cationic monomer, which requires careful fine-tuning as cationic polymers can potentially display toxicity to various cells. 32 The optimal amphiphilicity of the cationic polymer is considered to be a crucial factor for good antibacterial activity and minimal cytotoxicity. [33][34][35][36] Therefore, the cationic charge or hydrophobicity of side chains in various cationic-amphiphilic polymers should be well controlled in order to achieve the best antimicrobial activity.…”