A Hollow-Tube-Like Hydrospongel for Magnetothermal-Chemo-Chemodynamic Therapies in Advanced Colorectal Cancer Patients
Zhenning Wang,
Tao Wu,
Tenghui Li
et al.
Abstract:In advanced-stage colorectal cancer (CRC) treatments, preserving anal function presents significant challenges. This study introduces a novel hollow-tube-like hydrospongel (HTHSG), offering a groundbreaking approach to neoadjuvant therapy. Constructed from cellulose nanofibers crosslinked with Fe3O4@PDA nanoparticles, the HTHSG combines the rapid swelling characteristics of sponges (~ 10 seconds) with the robust fracture strength of hydrogels (> 250 kPa). Its unique design ensures stability and location ret… Show more
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