A hollow microshuttle-shaped capsule covalent organic framework for protein adsorption

Abstract

A hollow microshuttle-shaped capsule COF was prepared using a template-free procedure for the first time and has demonstrated the highest adsorption capacity (550.82 mg g−1) for hemoglobin so far.

Nanoscale covalent organic frameworks as theranostic platforms for oncotherapy: synthesis, functionalization, and applications

“…Host-guest encapsulation is a versatile and effective modication strategy to endow COFs with more functions, which utilizes accessible and permanent pores of COFs to capture guest molecules, including a variety of functional inorganic molecules, [382][383][384][385][386] organic molecules, [387][388][389] and even biological macromolecules. [390][391][392][393] The structural basis of host-guest encapsulation is the pores of COFs, which have unique characteristics. 394,395 First, the pores of COFs have a precise polygonal reticular structure with well-dened angles.…”

“…Due to the large and regular pores of COFs, the controlled loading and release of enzymes on the COF platform allows the enzyme to remain viable under harsh environmental conditions, which is imperative for enzyme catalysis and undoubtedly expands the application ranges of the enzymes. 392,393 Meanwhile, the chemical modication of the pore walls of COFs can easily regulate the pore environment, thereby improving the interaction and compatibility of COFs with specic enzymes, as well as optimizing the orientation of the active sites of the enzyme, thereby further improving the catalytic activity of the enzymes. 391…”

Covalent Organic Frameworks for Water Treatment

“…Beyond toxic heavy metal and radionuclide ion capture, there are several reports on COFs as adsorbents for lanthanide ions (Nd 3+ ), [ 98 ] perrhenate (ReO 4 − ), [ 99 ] phosphorus (PO 4 3− ), [ 100 ] arsenic (AsO 4 3− ), [ 100 ] organic compounds, [ 66,67,101–104 ] and even proteins. [ 105 ] Valtchev's group reported a carboxy‐functionalized COF (3D‐COOH‐COF) through the postsynthetic modification method and applied the 3D‐COOH‐COF in selective adsorption for lanthanide ion Nd 3+ over Sr 2+ and Fe 3+ . [ 98 ] Da et al.…”

Redox-active, luminescent coordination nanosheet capsules containing magnetite

“…Films can be directly synthesized by a reaction at the liquid-liquid or gas-liquid interface, where metal ions and organic ligands exist in different phases. Most previous work on CONASHs has used planar interfaces to obtain planar films; however, other spherical functional nanomaterials have been extensively studied [19][20][21][22][23][24][25][26][27][28][29][30][31] .…”