A history-dependent integrase recorder of plant gene expression with single cell resolution
Cassandra J. Maranas,
Wesley George,
Sarah K. Scallon
et al.
Abstract:During development, most cells experience a progressive restriction of fate that ultimately results in a fully differentiated mature state. Understanding more about the gene expression patterns that underlie developmental programs can inform engineering efforts for new or optimized forms. Here, we present a four-state integrase-based recorder of gene expression history and demonstrate its use in tracking gene expression events in Arabidopsis thaliana in two developmental contexts: lateral root initiation and s… Show more
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