A Histopathological Study of Malignant Lesions of the Female Breast in a Tertiary Care Centre

Jangid, Priya; Jangid, Mahendra Kumar; Pachori, Geeta

doi:10.14260/jemds/2020/392

Cited by 2 publications

(3 citation statements)

References 8 publications

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Section: Discussionsupporting

confidence: 92%

“…In our study, the peak incidence was seen in the age group 41-50 years (36.4%), which was similar to the studies by Yogalakshmi et al [11], Nandam et al [12] and Jangid et al [13]. The most common quadrant involved was upper outer, which included 34.5% of the carcinomas, followed by central quadrant (25.5%), which was comparable to the studies by Anushree et al [14] (upper outer 30% and central 17%), and Jangid et al [13] (upper outer 30.19%). Among the various histological types, the most common in our study was IDC NST (86.4%), which corresponds with studies by Anushree et al [14] (60%), Yogalakshmi et al [11] (77%), Eke et al [15] (88.6%) and Nandam et al [12].…”

Section: Discussionsupporting

confidence: 92%

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Histopathological Spectrum of Breast Carcinoma in a Tertiary Care Centre and its Association with ABO Blood Grouping and Rh Typing

Mitila

Subramanian

Srinivasan

et al. 2021

JPRI

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Background: Globally, breast cancer contributes to 27.7% of the newly diagnosed cases of cancer among women. Early screening and timely diagnosis of the lesions of breast help in alleviating the anxiety among patients. Histopathology is the gold standard in diagnosing the lesions, assessing the adequacy of treatment, and in disease prognosis. Studies have shown that ABO blood type has been associated with risk and survival for several malignancies. However, data for an association with breast cancer are inconsistent. Aim: To study the histopathological spectrum breast carcinomas and to investigate the presence of a possible association between breast cancer in women and ABO blood group and Rh factor. Materials and Methods: This retrospective descriptive study was done for a period of 4 years on 110 mastectomy specimens histopathologically diagnosed as breast cancers, and clinico-pathological data collected and analysed with records from the Department of Pathology, Saveetha Medical College. Association of breast cancer with ABO blood grouping and Rh typing was studied. Results: Left breast was involved in most cases (96.4%). The mean age was 50.86 years, with 41-50 years age group showing peak incidence. Infiltrating breast carcinoma, no special type (89.6%) was the most common histological type. ER and PR positivity was seen in 46.4% and 41.8% of cases respectively. A statistically significant association was seen between hormone receptor status and histological grade. 39.1% cases belonged to O blood group, and Rh positivity was seen in 96.4% of the cases. No association was found between breast cancer and ABO/Rh blood grouping.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

Histopathological Spectrum of Breast Carcinoma in a Tertiary Care Centre and its Association with ABO Blood Grouping and Rh Typing

Mitila

Subramanian

Srinivasan

et al. 2021

JPRI

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“…Breast cancer accounts for near one-quarter of all cancers in Indian females and about half of all cancer related mortality. With rising incidence and awareness, breast cancer is the most common cancer diagnosed in urban Indian females and the second most common in rural Indian females [2] . Breast cancer in younger patients have often been found to be associated with more aggressive behaviour, advanced disease at presentation and poorer overall survival particularly in low-and middle-income countries [3] .…”

Section: Introductionmentioning

confidence: 99%

Histopathological study of 300 breast lesions at rural tertiary care centre

Kute,

Swami

2022

Int. J. Clin. Diagn. Pathol.

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Introduction: A breast lesion biopsy procedure is a gold standard for the diagnostic evaluation of breast lesions with primary aim to identify the cause, especially to determine whether carcinoma or premalignant lesions are present. Painful breast lump is the commonest presenting symptom in surgery out-patient department. Here, we are presenting a study of 300 breast biopsies studied histologically at rural tertiary care centre. Objectives: This study was done to evaluate 300 breast lesion samples histopathologically at a rural tertiary care centre. Material and Methods: A total of 300 breast biopsies were processed and H & E staining was done. Special staining and IHC was done wherever required. Histopathological correlation was done in all the cases and the results were compared to other studies. Results: In our study of 300 breast lesions, the minimum age observed was 08 years and maximum age of 90 years with a male to female ratio of 1:18. The most common lesion in our study was benign neoplasms of breast of which fibroadenoma was predominant and observed in the age group 20-29 years followed by next common lesion as breast malignancies observed in the age group of 60-69 years. Conclusion: Histopathological examination of breast tissue is an important tool to diagnose various breast lesions. It is important to know the histological pattern of various breast lesions in the different age group patients, as it will help to differentiate inflammatory from neoplastic lesions, benign from malignant lesions and helps in the prognosis and management of the cases.

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A Histopathological Study of Malignant Lesions of the Female Breast in a Tertiary Care Centre

Cited by 2 publications

References 8 publications

Histopathological Spectrum of Breast Carcinoma in a Tertiary Care Centre and its Association with ABO Blood Grouping and Rh Typing

Histopathological Spectrum of Breast Carcinoma in a Tertiary Care Centre and its Association with ABO Blood Grouping and Rh Typing

Histopathological study of 300 breast lesions at rural tertiary care centre

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