BACKGROUND Splenectomy is a rare surgical procedure performed worldwide. It is performed as an emergency procedure, especially in cases of traumatic injury and as an elective procedure for other causes. Apart from primary pathology involving spleen, splenectomy is performed for other disorders like pancreatitis and malignancy of stomach when secondary involvement of spleen is suspected. Haematologic disorders, both malignant and non-malignant, are other important indications for splenectomy. Worldwide studies have shown that trauma (45-75%) is the leading cause of splenectomy in low income countries and during wars, while haematologic causes (20-35%) account for majority of splenectomy in high income countries. Very few studies have been carried out in India, especially South India to analyse splenectomy causes and histomorphology. Aim-This study is a two-year retrospective descriptive study done on splenectomy specimens