A highly selective and sensitive fluorescent turn-on Al³⁺ chemosensor in aqueous media and living cells: experimental and theoretical studies

Abstract

A highly selective and sensitive fluorescent chemosensor exhibited enhanced fluorescence in the presence of Al3+ and in living cells.

A Novel Thiophene-Based Fluorescent Chemosensor for the Detection of Zn2+ and CN−: Imaging Applications in Live Cells and Zebrafish

“…To elucidate the detection process of compound DHADC with CN − , we carried out the titration experiments of 1 H NMR ( Figure S13). The proton of the hydroxyl component did not show up because of the possible inter or intra-molecular hydrogen bonds [55]. With the addition of CN (2 equiv.)…”

A chemosensor for Al3+ ions in aqueous ethanol media: photophysical and live cell imaging studies

“…Both 1 H NMR (500 MHz) and 13 C NMR (125 MHz) spectra of the compounds were recorded on a JEOL JNM-LA500 FT spectrometer in CDCl 3 with tetramethylsilane as the internal standard. The ESI-mass data were obtained in acetonitrile using a WATERS-Q-TOF Premier Mass Spectrometer.…”

“…28 Also the calculated value of detection limit is found to lie in comparable range (1.0 Â 10 À6 M) for the reported Al 3+ sensors. 13,[29][30][31][32][33][34] Reversibility of uorescence is an imperative characteristic in developing chemosensors for practical aspects. The reversible nature of the sensor L is checked by adding an aqueous solution of Na 2 EDTA to the solution of metal complex.…”

“…[9][10][11] Several rhodamine derivatives have been reported as sensors for the Al 3+ ions. [12][13][14][15][16][17] Most of them are functional only in organic solvents due to strong hydration of Al 3+ in water thus making them difficult for practical applications. 18 To increase aqueous solubility of the chemosensor, 2-methoxy-4-nitroaniline group, has been appended as the receptor to the rhodamine B moiety (Scheme 1) as it can increase the hydrophilic interaction by enhancing the polar character in the molecule.…”

“…18 To increase aqueous solubility of the chemosensor, 2-methoxy-4-nitroaniline group, has been appended as the receptor to the rhodamine B moiety (Scheme 1) as it can increase the hydrophilic interaction by enhancing the polar character in the molecule. 19 The dye is well-characterized by 1 H-and 13 C-NMR spectroscopy, single crystal X-ray diffraction, ESI-mass spectrometry and elemental analyses. It acts as a uorescence turn-on chemosensor for the Al 3+ ion in aqueous ethanol medium.…”