A Highly Selective and Sensitive Peptide-Based Fluorescent Ratio Sensor for Ag+

Pyrene-Modified Cyclic Peptides Detect Cu2+ Ions by Fluorescence in Water

“…Ramezanpour et al reported that trimeric Ser-Glu-Glu and heptameric Ala-Glu-Pro-Glu-Ala-Glu-Pro modified with a 2-aminobenzoyl group selectively detected Al 3+ by fluorescence emission through 1:1 binding (K d = 7.7 × 10 −5 and 5.7 × 10 −5 M, respectively) in aqueous solution [9]. Li et al reported that a pentameric peptide, Glu-Cys-Glu-Glu-Trp, modified with a dansyl group (Dns), selectively detected Ag + by ratiometric and turn-on fluorescence emission through 1:1 binding (K d = 6.4 × 10 −9 M) in aqueous solution [10]. Finally, Lee et al reported that a decameric peptide, Ala-Ala-Cys-Ala-Ala-His-Cys-Trp-Ala-Glu, modified with a Dns, detected Cd 2+ , Pb 2+ , Zn 2+ , or Ag + by ratiometric and turn-on fluorescence emission through 2:1 binding (K d = 2.6−4.5 × 10 −10 M 2 ) in aqueous solution [11].…”

Graphene Bioelectronic Nose for the Detection of Odorants with Human Olfactory Receptor 2AG1

“…Synthetic peptide chains have also been utilized to selectively and sensitivity detect various odorants, for example in piezoelectric sensors using immobilized peptide chains based on the odorant-binding region of HarmOBP7 [26,27]. Similarly, a synthetic peptide fluorescent ratio sensor based on dansyl-peptide was recently demonstrated to selectively detect Ag + against other common metal ions as low as 80 nM in water treatment applications [28]. In another example, peptide hormone sensors were realized using human hormone receptor-carrying nanovesicles immobilized on graphene-FET devices [29].…”