A highly efficient molecularly imprinted fluorescence sensor for assessing whole wheat grains by the rapid and sensitive detection of alkylresorcinols

Molecularly Imprinted Electrochemical Sensor Based on α-Cyclodextrin Inclusion Complex and MXene Modification for Highly Sensitive and Selective Detection of Alkylresorcinols in Whole Wheat Foods

“…Specifically, adsorption peaks at 2987, 2950, and 1718 cm –1 were attributed to the vibrations of methyl–CH 3 , methylene–CH 2 , and the carbonyl group (CO) of EGDMA. Additionally, adsorption peaks at 3364 and 1390 cm –1 corresponded to the characteristic absorptions of AM, detected in all three samples. Notably, in the DMIP spectrum, a strong band at 3600–3000 cm –1 and an adsorption band at 1018 cm –1 were observed, attributed to the O–H stretching, CO stretching, and C–O–C stretching vibrations of α-CD .…”

“…Subsequently, DMIP/MXene/GE was immersed in the extract for 30 min, and the electrochemical responses of the electrode before and after incubation were recorded. For comparison, the HPLC method was also employed for AR21 detection, following the detailed procedure from our previous work …”

“…For comparison, the HPLC method was also employed for AR21 detection, following the detailed procedure from our previous work. 16…”

“…15 It has been widely utilized to enhance sensor selectivity due to its specific recognition ability, ease of preparation, low cost, and physical robustness. 16 However, in most MIP preparation methods, only a single functional monomer is employed and the single interaction force may sometimes be insufficient to achieve favorable recognition in a complex system. Research has shown that using two different functional monomers can create multiple interactions between MIP cavities and template molecules, thus providing stronger selectivity and affinity.…”

“…Molecularly imprinted polymer (MIP) is a synthetic material designed to mimic the specific binding of antigens and antibodies, offering high selectivity through the memory of shape, size, and three-dimensional complementary cavities of a template molecule . It has been widely utilized to enhance sensor selectivity due to its specific recognition ability, ease of preparation, low cost, and physical robustness . However, in most MIP preparation methods, only a single functional monomer is employed and the single interaction force may sometimes be insufficient to achieve favorable recognition in a complex system.…”