A high-resolution X-ray microscope system for performance evaluation of scintillator plates

Yamamoto, Seiichi; Yoshino, Masao; Kamada, Kei; Yajima, Ryuga; Yoshikawa, Akira; Sagisaka, Mayu; Kataoka, J.

doi:10.1088/1748-0221/17/09/t09012

Cited by 7 publications

(5 citation statements)

References 17 publications

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“…Recently, we developed a high-resolution and high-efficiency performance evaluation system of scintillators for X-rays 12 . The imaging system could achieve a spatial resolution of up to approximately 1 µm when we combined it with micro-focus X-rays or synchrotron radiations.…”

Section: Introductionmentioning

confidence: 99%

Development of an ultrahigh resolution real time alpha particle imaging system for observing the trajectories of alpha particles in a scintillator

Yamamoto

Yoshino

Kamada

et al. 2023

Sci Rep

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High-resolution imaging of alpha particles is required in the detection of alpha radionuclides in cells or small organs for the development of radio-compounds for targeted alpha-particle therapy or other purposes. We developed an ultrahigh resolution, real time alpha-particle imaging system for observing the trajectories of alpha particles in a scintillator. The developed system is based on a magnifying unit and a cooled electron multiplying charge-coupled device (EM-CCD) camera, combined with a 100-µm-thick Ce-doped Gd3Al2Ga3O12 (GAGG) scintillator plate. Alpha particles from an Am-241 source were irradiated to the GAGG scintillator and imaged with the system. Using our system, we measured the trajectories of the alpha particles having different shapes in real time. In some of these measured trajectories, the line shapes of the alpha particles that flew in the GAGG scintillator were clearly observed. The lateral profiles of the alpha-particle trajectories were imaged with widths of ~ 2 µm. We conclude that the developed imaging system is promising for research on targeted alpha-particle therapy or other alpha particle detections that require high spatial resolution.

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Section: Introductionmentioning

confidence: 99%

Development of an ultrahigh resolution real time alpha particle imaging system for observing the trajectories of alpha particles in a scintillator

Yamamoto

Yoshino

Kamada

et al. 2023

Sci Rep

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“…We previously combined a fiber-structured scintillator plate and a high-sensitivity CCD camera to observe the trajectories of alpha particles [16,17]. We also developed a high-resolution, real-time performance evaluation system of scintillators for X-rays by combining scintillators with a highsensitivity CCD camera [19,20]. We conjectured that these systems could be applied to imaging the trajectories of neutron induced particles if we employed the system in combination with a Li-ZnS(Ag) plate.…”

Section: Introductionmentioning

confidence: 99%

A high-resolution real-time imaging system for observing the trajectories of neutron induced particles in a scintillator

et al. 2023

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High-resolution imaging of neutron induced particles is required in such methods as neutron radiography. However, the scintillation spots in a neutron-sensitive scintillator have not yet been imaged nor measured for size. We developed a high-resolution, real-time neutron induced particle imaging system for observing these particles' trajectories in a scintillator. The developed system is based on a magnifying unit and a cooled electron multiplying charge-coupled device (EM-CCD) camera combined with a lithium-containing silver-doped zinc sulfide (Li-ZnS(Ag)) scintillator plate. Neutrons from a californium-252 (252Cf) source were irradiated to the Li-ZnS(Ag) scintillator and imaged with the system. Using our system, we measured the scintillation spots of the neutron induced particles having different shapes in real time. In some of these measured scintillation spots, those with elliptical shapes were observed due to the trajectories of the particles in the scintillator. The spatial resolution calculated from the widths of the scintillation spots was ∼56 μm. Consequently, the developed imaging system is promising for research on neutron imaging that requires high spatial resolution.

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“…The imaging system adopted a magnifying unit commonly used to measure high-resolution transmission images combined with synchrotron radiations that can achieve sub-micrometer spatial resolution [13]. The magnifying unit was also used for a high-efficiency performance-evaluation system of scintillators for X-rays [14,15].…”

Section: Introductionmentioning

confidence: 99%

Sub-micrometer real-time imaging of trajectory of alpha particles using GAGG plate and CMOS camera

Yamamoto,

Yoshino,

Nakanishi

et al. 2023

J. Inst.

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High-resolution and real-time imaging of the trajectories of alpha particles is desired in nuclear medicine and nuclear engineering. Although an imaging method using a scintillator plate combined with a magnifying unit and a cooled electron multiplying charge-coupled device (EM-CCD) camera is a possible method of obtaining high-resolution trajectory images, the spatial resolution of the system is limited to ∼2 μm. To overcome the spatial resolution limitations of this method on trajectory imaging, we used a cooled complementally metal oxide (CMOS) camera in which the sensor had a much larger number of pixels, which were also smaller. Using the CMOS camera based imaging system, we could measure the trajectories of alpha particles in real time with the spatial resolution of 0.34 μm FWHM. With smoothing of the images to reduce image noise, spatial resolution was still kept to less than 0.75 μm. We conclude that this CMOS camera-based alpha-particle trajectory-imaging system is promising for alpha-particle or other particles imaging where ultrahigh spatial resolution is required.

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A high-resolution X-ray microscope system for performance evaluation of scintillator plates

Cited by 7 publications

References 17 publications

Development of an ultrahigh resolution real time alpha particle imaging system for observing the trajectories of alpha particles in a scintillator

Development of an ultrahigh resolution real time alpha particle imaging system for observing the trajectories of alpha particles in a scintillator

A high-resolution real-time imaging system for observing the trajectories of neutron induced particles in a scintillator

Sub-micrometer real-time imaging of trajectory of alpha particles using GAGG plate and CMOS camera

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