A high resolution PET for animal studies

Abstract

In the PET system a block detector, which is a position-sensitive photomultiplier (PMT) tube coupled to four arrays of 1.7-mm-wide BGO crystals, is utilized. Fifteen block detectors are positioned to form a 35-cm-diameter ring, with four BGO arrays coupled to each PMT. This provides four detector rings, giving the system a 7-slice imaging capability. The gantry head tilts up to +/-90 degrees , and is capable of moving up and down by 30 cm. These positioning capabilities allow flexibility and great ease of use in subject positioning. A gantry entrance size of 22 cm in diameter allows studies ranging from rats and mice to primates such as Rhesus and squirrel monkeys. The physical performance of the system has been evaluated.

Performance characteristics of a compact position-sensitive LSO detector module

“…[3][4][5] show that apparent row and column separations agree with this prediction. Moving away from the image center, apparent crystal separation shrinks as the center of the firs anode is approached, then expands in the next interplate gap, then shrinks again as the outer anode plate is approached.…”

Visualization of Sigma1 Receptors in Eyes by ex vivo Autoradiography and in vivo Positron Emission Tomography

“…9±2 . 2 kg with a model SHR-2000 camera (Hamamatsu Photonics K. K., Hamamatsu, Japan) (Watanabe et al, 1992) with the Z 2 mode which gave 14 slices at 3 . 25 mm intervals (Ishiwata et al, 1999a).…”

Copyright

“…Small animal PET systems based on rotating planar detectors are an alternative, cost effective research tool for molecular imaging, and posses some interesting advantages for high sensitivity, high resolution imaging [1][2][3][4][5][6][7][8][9]. The planar detectors are usually built around compact sensors with a high accuracy in the location of the event.…”