A hemostatic keratin/alginate hydrogel scaffold with methylene blue mediated antimicrobial photodynamic therapy

Abstract

Uncontrollable bleeding and infection are two of the most common causes of trauma-related death. Yet, developing safe materials with high hemostatic and antibacterial effectiveness remains a challenge. Keratin-based biomaterials have...

Bioactive Hydrogels with Pro‐coagulation Effect for Hemostasis†

“…The combination of these multiple effects has improved the hemostatic performance of this material. Platelets can also be captured and enriched using polyphenols, [ 195 ] keratin, [ 196 ] and other materials. [ 197 ] In addition to directly capturing platelets, hemostasis can be achieved by activating platelet receptors using peptides [ 158‐159 ] or designing platelet‐mimicking materials [ 198 ] to enhance or mimic platelet function.…”

Switchable adhesive films of pullulan loaded with a deep eutectic solvent-curcumin formulation for the photodynamic treatment of drug-resistant skin infections

“…The advantage of these systems is the dual capacity for being used as both bandage material and delivery system, while providing a moist healing environment [ 9 , 10 ]. Hydrogels originated from natural polymers, such as alginate [ 11 ], keratin [ 11 ] and chitosan [ 12 , 13 ], have been applied for aPDT purposes. Adhesive hydrogel films have the advantage of extending the residence time, allowing to prolong the local therapeutic action [ 14 ].…”