The life-span of corpora lutea (cl) of varying ages within the one rabbit was studied by an experimental procedure in which 2-day\ x=req-\ old cl removed from donor rabbits were transferred beneath the kidney capsule of recipient rabbits. Within oestrous recipients, the cl were found to have a total life-span of approximately 17 days, which was similar to that of ovarian cl in the pseudopregnant rabbit. When the cl were transferred into 12-day pseudopregnant rabbits, their life-span was reduced to approximately 11 days and both the ovarian and transferred cl regressed at approximately the same time. It was suggested that a uterine factor may have caused the early regression of the transferred cl since hysterectomy at the time of transfer prolonged the life-span of each set of cl to approximately 23 to 27 days. In these animals, the cl regressed asynchronously.Prostaglandin F2\g=a\ caused early regression of the ovarian cl when given to hysterectomized rabbits.