A HAK family Na+ transporter confers natural variation of salt tolerance in maize

Zhang, Ming; Liang, Xiaoyan; Wang, Limin; Cao, Yibo; Song, Weibin; Shi, Junpeng; Lai, Jinsheng; Jiang, Caifu

doi:10.1038/s41477-019-0565-y

Cited by 158 publications

(148 citation statements)

References 64 publications

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“…Although SOS1 is an important Na + /H + -antiporter that excludes Na + from the cytosol, and much work has been devoted to characterizing the SOS pathway, other sodium transporters such as Arabidopsis HIGH-AFFINITY K + TRANSPORTER1 (HKT1) (Uozumi et al, 2000;Ren et al, 2005;Munns et al, 2012;Zhang et al, 2018), and maize High affinity K + 4 (ZmHAK4) (Zhang et al, 2019c) also play important roles in salt tolerance. However, whether and how HKT1 and ZmHAK4 are regulated by protein kinases or other modifications is currently not well known.…”

Section: Other Protein Kinases In Salt Stressmentioning

confidence: 99%

“…Moreover, temperature fluctuations, including high and low temperatures, have marked adverse effects on crop productivity. For example, rice yield in the northeast region of China decreased by 42% in 1972 and by 37% in 1976, due to severe chilling stress (Zhang et al, 2019b). Similarly, wheat grain yield is estimated to diminish by 1%–1.6% for every °C increase per day over 30°C (Liu et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

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Protein kinases in plant responses to drought, salt, and cold stress

Chen

Ding

Yang

et al. 2021

JIPB

345

238

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Protein kinases are major players in various signal transduction pathways. Understanding the molecular mechanisms behind plant responses to biotic and abiotic stresses has become critical for developing and breeding climate-resilient crops. In this review, we summarize recent progress on understanding plant drought, salt, and cold stress responses, with a focus on signal perception and transduction by different protein kinases, especially sucrose non-fermenting1 (SNF1)-related protein kinases (SnRKs), mitogen-activated protein kinase (MAPK) cascades, calcium-dependent protein kinases (CDPKs/CPKs), and receptor-like kinases (RLKs). We also discuss future challenges in these research fields.

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Section: Other Protein Kinases In Salt Stressmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Protein kinases in plant responses to drought, salt, and cold stress

Chen

Ding

Yang

et al. 2021

JIPB

345

238

View full text Add to dashboard Cite

show abstract

“…Salinity stress has also been found to upregulate the Arabidopsis root K + transporter gene ( AtKC1 ), KMT1 (AKT/KAT family member) and various HAK/KUP genes, whereas MKT1 (AKT/KAT family member) gene is downregulated for effective K + transport (Conde et al 2011). A recent study identified a major QTL ZmNC2/ZmHAK4 regulating shoot Na + exclusion and salt tolerance in maize (Zhang et al 2019). Furthermore, the ZmHAK4 has been revealed to be mainly expressed in root stele, encoding Na + selective transporter that eliminates shoot Na + from xylem sap.…”

Section: Maintenance Of Cytosolic K+mentioning

confidence: 99%

Reassessing the role of ion homeostasis for improving salinity tolerance in crop plants

Basu

Kumar

Benazir

et al. 2020

Physiologia Plantarum

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Soil salinity is a constraint for major agricultural crops leading to severe yield loss, which may increase with the changing climatic conditions. Disruption in the cellular ionic homeostasis is one of the primary responses induced by elevated sodium ions (Na+). Therefore, unraveling the mechanism of Na+ uptake and transport in plants along with the characterization of the candidate genes facilitating ion homeostasis is obligatory for enhancing salinity tolerance in crops. This review summarizes the current advances in understanding the ion homeostasis mechanism in crop plants, emphasizing the role of transporters involved in the regulation of cytosolic Na+ level along with the conservation of K+/Na+ ratio. Furthermore, expression profiles of the candidate genes for ion homeostasis were also explored under various developmental stages and tissues of Oryza sativa based on the publicly available microarray data. The review also gives an up‐to‐date summary on the efforts to increase salinity tolerance in crops by manipulating selected stress‐associated genes. Overall, this review gives a combined view on both the ionomic and molecular background of salt stress tolerance in plants.

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“…OsHAK1, OsHAK5, OsHAK16 and OsHAK21 can coordinately regulate Na + /K + homeostasis and the membrane potential of root cells under salt conditions [ 4 , 8 , 9 , 18 , 19 ]. A genome-wide association (GWAS) study in Zea mays L. showed ZmHAK4-mediated shoot K + /Na + homeostasis for improving salt tolerance, conferring the natural variation of this gene [ 20 ]. Therefore, under saline conditions, K + nutrition largely depends on HAK/KUP/KT system, affecting agriculture worldwide.…”

Section: Introductionmentioning

confidence: 99%

Halophytic Hordeum brevisubulatum HbHAK1 Facilitates Potassium Retention and Contributes to Salt Tolerance

Zhang

Xiao

et al. 2020

IJMS

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Potassium retention under saline conditions has emerged as an important determinant for salt tolerance in plants. Halophytic Hordeum brevisubulatum evolves better strategies to retain K+ to improve high-salt tolerance. Hence, uncovering K+-efficient uptake under salt stress is vital for understanding K+ homeostasis. HAK/KUP/KT transporters play important roles in promoting K+ uptake during multiple stresses. Here, we obtained nine salt-induced HAK/KUP/KT members in H. brevisubulatum with different expression patterns compared with H. vulgare through transcriptomic analysis. One member HbHAK1 showed high-affinity K+ transporter activity in athak5 to cope with low-K+ or salt stresses. The expression of HbHAK1 in yeast Cy162 strains exhibited strong activities in K+ uptake under extremely low external K+ conditions and reducing Na+ toxicity to maintain the survival of yeast cells under high-salt-stress. Comparing with the sequence of barley HvHAK1, we found that C170 and R342 in a conserved domain played pivotal roles in K+ selectivity under extremely low-K+ conditions (10 μM) and that A13 was responsible for the salt tolerance. Our findings revealed the mechanism of HbHAK1 for K+ accumulation and the significant natural adaptive sites for HAK1 activity, highlighting the potential value for crops to promote K+-uptake under stresses.

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A HAK family Na+ transporter confers natural variation of salt tolerance in maize

Cited by 158 publications

References 64 publications

Protein kinases in plant responses to drought, salt, and cold stress

Protein kinases in plant responses to drought, salt, and cold stress

Reassessing the role of ion homeostasis for improving salinity tolerance in crop plants

Halophytic Hordeum brevisubulatum HbHAK1 Facilitates Potassium Retention and Contributes to Salt Tolerance

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