Background Recently, the infra-acetabular screw was proposed for acetabular fractures as a part of a periacetabular fixation frame. Biomechanical studies showed that an additional infra-acetabular screw placement can enhance the fixation strength of acetabular fracture internal fixation. At present, the reported exit point of the infra-acetabular screw was all located at the ischial tuberosity. However, through great experience in placing the infra-acetabular screw, we realized that when the exit point was located between the ischial tuberosity and the ischial spine, the placement of a 3.5 mm infra-acetabular screw is easier in some patients. Methods This study used axial perspective based on 3D models to study the anatomical parameters of the two different infra-acetabular screw corridors. Placed the largest diameter virtual screw in the two different screw corridors. The data obtained in this study present the maximum diameters, length, directions, and distances between the entry point and the center of IPE. Results In 65.31% males and 40.54% females, a Screw I corridor with a diameter of at least 5 mm was found, while in Screw II it was 77.55% in males and 62.16% in females. Compared with screw I, the length of screw II is reduced, the angle with the coronal plane is significantly reduced, and the angle with the transverse plane is significantly increased.Conclusions For East Asians, changing the exit point of the infra-acetabular screw can increase the scope of use of the infra-acetabular screw, especially for females.