A guanidinium modified rhodamine-based fluorescent probe for in vitro/vivo imaging of gold ions

Abstract

We devised a rhodamine-based fluorescent probe functionalized with a guanidinium moiety, which both operates efficiently in pure aqueous media and displays a selective fluorescence response to Au 3+ ions.We also demonstrated the successful fluorescence imaging of Au 3+ within living cells and a vertebrate species, the zebrafish.

An Anthracene and Indole-based Fluorescent Probe for the Detection of Chromium(III) Ions in Real Water Samples

“…There are several instruments for detecting trace chromium(III) ions, including atomic absorption spectroscopy (AES), atomic emission spectroscopy (AAS), and inductively coupled plasma mass spectroscopy (ICP-MS) [14][15][16][17][18][19]. On the other hand, uorescence approaches have received much attention compared to the mentioned methods above because of their great sensitivity and selectivity, low cost, ease of operation, and real-time detection [20][21][22][23][24]. For the detection of chromium(III) ions, various uorescent probes have been developed, such as rhodamine [25][26][27], Bodipy [28,29], coumarine [30], and anthracene [31,32]based uorescent probes.…”

A BODIPY based probe for the reversible "turn on" detection of Au(III) ions

“…Several fluorescent probes have been specifically designed to detect gold ions by utilizing fluorophores including BODIPY [ 17 , 18 ], Rhodamine [ 19 – 20 ], fluorescein [ 21 – 23 ], coumarin [ 24 ], and naphthalimide [ 25 ]. Most of these probes were constructed on irreversible reaction-based sensing strategies that are largely based on the alkynophilic character of gold ions [ 17 , 19 , 24 ] or hydrolysis of C = N bond [ 21 , 26 , 27 ].…”

A New Indole Substituted Biphenyldiamine Derivative Schiff Base: A New Sensor Application for the Selective Detection of Hg(II) Ions

“…Most of the main threats to life on earth are industrial waste which causes serious environmental problems as a result of their toxic substances released in the industrial processes [1]. Heavy metals, which are poisonous and non-degradable, are a major environmental contaminant and hence tending to build up through the food chain in animals and humans [2][3][4]. According to WHO's list concerning human health released in 2017, four heavy metals, including plum, cadmium, mercury and arsenic are listed as ten dangerous chemical substances or a combination of chemical products [5].…”