A green spectrophotometric method for the simultaneous determination of nasal binary mixture used in respiratory diseases: Applying isosbestic point and chemometric approaches as a resolving tool, greenness evaluation

Sustainable Stability-Indicating spectra manipulations for the concurrent quantification of a novel Anti-COVID-19 drug and its active Metabolite: Green profile assessment

“…The AGREE® program forms the backbone of the second system [35] , [36] , [37] . The 12 elements of Green Analytical Chemistry (GAC) are the basis for a clock-shaped graph provided by AGREE.…”

“…The green analytical procedure index, GAPI [36] , [37] , [38] was also utilized to evaluate green assessment. GAPI is made up of fifteen separate areas (five pentacle shapes) for estimating and evaluating the environmental impact of each step of any analytical process, beginning with preparation of sample and ending with instrumentation and waste quantity and treatment.…”

“…The analytical Eco-Scale [36] , [37] , [39] , [40] was also utilized to evaluate the greenness of the current spectrophotometric approaches for the concurrent analysis of MOL and NHC. This tool is a current comprehensive scale that calculates the penalty points (PPs) of any process's analytical parameters such as the nature and quantity of reagents, occupational hazards, the energy required, and waste generated.…”