A green-brown plaque on the dorsal hand

Persistent Green-Blue Plaque in a Healthy Woman

“…1 These tumors typically stain positive for CD34 and negative for desmin, smooth muscle actin, keratin, and S100. 2 While HFLTs predominantly occur on the foot and ankle, these tumors can also occur elsewhere on the body, including the hand and/or wrist in up to 10% of reported cases. [1][2][3][4][5][6][7] First described in 2000, the HFLT was initially thought to represent a reactive inflammatory process because 7 of these 8 reported cases had a history of trauma that occurred in the same area where the HFLT later occurred.…”

“…2 While HFLTs predominantly occur on the foot and ankle, these tumors can also occur elsewhere on the body, including the hand and/or wrist in up to 10% of reported cases. [1][2][3][4][5][6][7] First described in 2000, the HFLT was initially thought to represent a reactive inflammatory process because 7 of these 8 reported cases had a history of trauma that occurred in the same area where the HFLT later occurred. 1 Kazakov et al 8 proposed that vascular insufficiency contributes to HFLT pathogenesis, although the discovery of a chromosomal translocation t(1;10)(p22;q24) and/or TGFBR3/MGEA5 rearrangement(s) in 17 cases has suggested a potential primary neoplastic origin of this diagnosis.…”

“…The HFLT tumor is a rare, slow-growing painful subcutaneous mass characterized by varying proportions of mature adipocytes, spindle cells, and hemosiderin pigment . These tumors typically stain positive for CD34 and negative for desmin, smooth muscle actin, keratin, and S100 . While HFLTs predominantly occur on the foot and ankle, these tumors can also occur elsewhere on the body, including the hand and/or wrist in up to 10% of reported cases …”

“…These tumors typically stain positive for CD34 and negative for desmin, smooth muscle actin, keratin, and S100 . While HFLTs predominantly occur on the foot and ankle, these tumors can also occur elsewhere on the body, including the hand and/or wrist in up to 10% of reported cases …”