A green-based approach for noninvasive skin rejuvenation: Potential application of hyaluronic acid

Tanha, Amirabas; Rabiee, Mohammad; Rostami, Azin; Ahmadi, Sepideh

doi:10.1016/j.envres.2023.116467

Cited by 6 publications

(2 citation statements)

References 133 publications

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“…Other studies have suggested that the free radical scavenging nature of hyaluronic acid contributes to protection against UVB and UVA radiation, which supports the role of CD44 as a hyaluronic acid receptor in the epidermis [9,10]. The current popularity of hyaluronic acid as an ingredient in cosmetic products and in injectable aesthetic medical devices, alongside emerging research findings on its cellular effects, has instigated further studies [4,[20][21][22][23][24][25][26][27][28].…”

Section: Introductionmentioning

confidence: 88%

Current Knowledge and Regulatory Framework on the Use of Hyaluronic Acid for Aesthetic Injectable Skin Rejuvenation Treatments

Allen,

Dodou

2024

Cosmetics

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Dermal injections of hyaluronic acid gel for aesthetic skin rejuvenation are becoming increasingly popular nowadays. Although these products are classified as medical devices, the regulations on their administration by licensed practitioners are still weak, whereas their manufacturers increasingly highlight and advertise the cellular effects that underpin the efficacy of these injections. In this review, we discuss all current knowledge on the mode of action of dermally injected hyaluronic acid and the potential toxicological implications, especially from crosslinked gels, in conjunction with the current global regulations. We also highlight the urgent need for further research to elucidate the therapeutic implications and underscore the imperative need for robust regulatory frameworks to safeguard public health. We conclude that dermal injections of hyaluronic acid have several therapeutic implications that warrant further research and that strict regulations must be applied to their manufacture/quality control and the required qualifications of licensed aesthetic injectors.

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Section: Introductionmentioning

confidence: 88%

Current Knowledge and Regulatory Framework on the Use of Hyaluronic Acid for Aesthetic Injectable Skin Rejuvenation Treatments

Allen,

Dodou

2024

Cosmetics

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“…The goal of the skin rejuvenation process is to reduce the indications of aging by utilizing a combination of bio-revitalization techniques, skin-strengthening measures, and lifestyle modifications. The demand for noninvasive skin rejuvenation techniques is rising, and plastic surgeons need to be highly skilled in implementing new methods and tools in a safe and effective manner 10 .…”

Section: Introductionmentioning

confidence: 99%

Comparison the Effect of Fractional RF Laser with Microneedling on Facial Skin Rejuvenation, Open Pores and Skin Lightening: A Non-Randomized Controlled Clinical Trial

Mamizadeh,

Ghorabi,

Jamali

et al. 2024

WJPS

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Background: Effective skin rejuvenation treatments with RF technologies exist, with potential for personalized combination therapies based on individual factors. We compared microneedling and fractional RF laser effectiveness in rejuvenation, pore healing, and skin lightening. Method: The research was a non-randomized clinical trial study conducted in 2021 at Ilam Skin Clinic, Ilam, western Iran on people applying for rejuvenation, skin lightening and improvement of open pores. People were voluntarily divided into two groups based on personal preferences (group A: microneedling, 25 people, group B: fractional RF, 25 people). After data collection, SPSS22 software was used for data analysis. Results: The study revealed significant differences in the rates of low, moderate, and severe pain between the microneedling and fractional groups (10 vs. 16, 14 vs. 4, 1 vs. 5, respectively). Erythema showed no significant difference, with low, moderate, and severe cases reported in both groups. Swelling was lower in the microneedling group, but the difference was not significant. Bruising was similar in both groups, and staining was minimal. No herpes or infections were reported. The microneedling group showed better improvement in skin pores and skin lightening compared to the fractional group, with outcomes rated as good and excellent. Conclusion: Microneedling surpassed the fractional group in skin rejuvenation, lightening, and improved pores. Considering RF lasers are approximately three times more expensive than microneedling, the research indicates that choosing microneedling is not only more cost-effective but also a superior rejuvenation technique.

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Contribution of chemical permeation enhancers to the process of transdermal drug delivery: Adsorption, microscopic interactions, and mechanism

Jiang,

Liu,

Zhang

et al. 2024

Colloids and Surfaces B: Biointerfaces

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A green-based approach for noninvasive skin rejuvenation: Potential application of hyaluronic acid

Cited by 6 publications

References 133 publications

Current Knowledge and Regulatory Framework on the Use of Hyaluronic Acid for Aesthetic Injectable Skin Rejuvenation Treatments

Current Knowledge and Regulatory Framework on the Use of Hyaluronic Acid for Aesthetic Injectable Skin Rejuvenation Treatments

Comparison the Effect of Fractional RF Laser with Microneedling on Facial Skin Rejuvenation, Open Pores and Skin Lightening: A Non-Randomized Controlled Clinical Trial

Contribution of chemical permeation enhancers to the process of transdermal drug delivery: Adsorption, microscopic interactions, and mechanism

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