A Gold Nanoparticle‐Based Fluorescence Turn‐On Probe for Highly Sensitive Detection of Polyamines

Kim, Tae Il; Park, Jihye; Kim, Youngmi

doi:10.1002/chem.201102060

Cited by 51 publications

(29 citation statements)

References 27 publications

(23 reference statements)

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“…Thirdly, since the electrostatic effect is much weaker than S‐Au and N‐Au interaction, it could be replaced by both nitrogen and thiol group involving derivatives. Therefore, a useful platform was developed by cationic BODIPY derivative‐AuNPs system for selective and sensitive detection of spermine and spermidine over other structurally similar amines with a LOD of 10 −7 M . Further, positive charged rhodamine B was directly used in Hg 2+ detection, based on the fact that electrostatic effect is much weaker than the metal‐metal interaction between Hg‐Au .…”

Section: Fluorescent Probes Based On Aunps/ncsmentioning

confidence: 99%

Optical Reading of Contaminants in Aqueous Media Based on Gold Nanoparticles

Zhu

Peng

et al. 2014

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With increasing trends of global population growth, urbanization, pollution over-exploitation, and climate change, the safe water supply has become a global issue and is threatening our society in terms of sustainable development. Therefore, there is a growing need for a water-monitoring platform with the capability of rapidness, specificity, low-cost, and robustness. This review summarizes the recent developments in the design and application of gold nanoparticles (AuNPs) based optical assays to detect contaminants in aqueous media with a high performance. First, a brief discussion on the correlation between the optical reading strategy and the optical properties of AuNPs is presented. Then, we summarize the principle behind AuNP-based optical assays to detect different contaminants, such as toxic metal ion, anion, and pesticides, according to different optical reading strategies: colorimetry, scattering, and fluorescence. Finally, the comparison of these assays and the outlook of AuNP-based optical detection are discussed.

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Section: Fluorescent Probes Based On Aunps/ncsmentioning

confidence: 99%

Optical Reading of Contaminants in Aqueous Media Based on Gold Nanoparticles

Zhu

Peng

et al. 2014

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“…Conventional methods for the determination of histamine (e.g., chromatography, capillary electrophoresis, fluorimetry, and immunoassays) mostly involve complex, multistep sample preparation procedures and expensive instruments, which limits their application in the real life sample analysis . On the other hand, small‐molecule‐based optical probes for biogenic amines typically suffer from problems such as poor selectivity and weak response in aqueous media . Although the specificity towards histamine could be improved by engaging transition‐metal complexes as the interactive systems [M 2+ =Zn 2+ or Ni 2+ etc.…”

Section: Introductionmentioning

confidence: 99%

“…[12][13][14][15] On the other hand, small-molecule-based optical probes for biogenic amines typically suffer from problems such as poor selectivity and weak response in aqueous media. [16][17][18][19][20][21][22][23][24] Although the specificity towards histamine could be improved by engaging transition-metal complexes as the interactive systems [M 2 + = Zn 2 + or Ni 2 + etc. ],t hese sensors are generally unsuitable for biological applicationsb ecause of their high cytotoxicity (Figure 1a).…”

Section: Introductionmentioning

confidence: 99%

Dual‐Mode Optical Sensing of Histamine at Nanomolar Concentrations in Complex Biological Fluids and Living Cells

Dey

Ali

Podder

et al. 2017

Chemistry A European J

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An easily synthesized fluorescein-based luminescent dye has been utilized for the dual-mode detection of histamine at nanomolar concentrations at pH 7.0 in water. The specific response to histamine was achieved by imidazole-catalyzed 'imine formation' reaction. The protocol was subsequently applied for the estimation of histamine in complex biological milieu such as human blood serum and urine samples. Furthermore, the dose-dependent cellular uptake of histamine and de novo synthesis (by thapsigargin treatment) was visualized in RAW 264.7, a mouse macrophage cell line. We have also developed portable paper strips for rapid, on-site detection of histamine without involving costly instruments.

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“…Because such polyamines lack useful UV-Visible spectroscopic signatures themselves, systems capable of displaying spectroscopic changes in response to the presence of such analytes are necessary. Several examples of colorimetric and/or turn-on fluorescence sensors have been established, driven by the interactions of small molecule chromophores, [12–15] organic polymers, [16, 17] coordination compounds [18] and nanoparticles [19–21] with polyamine analytes of interest. Unfortunately, the majority of these methods have shown a limited ability to discriminate among spermine, spermidine, putrescine and cadaverine analytes.…”

Section: Introductionmentioning

confidence: 99%

Spermine detection via metal-mediated ethynylarene ‘turn-on’ fluorescence signaling

Fletcher

Bruck

2015

Sensors and Actuators B: Chemical

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A dicarboxylated ethynylarene was shown to behave as a fluorescent chemosensor for millimolar concentrations of polyamines when mixed with Cd(II), Pb(II) or Zn(II) ions at micromolar concentrations. A bathochromic shift and intensification of fluorescence emission was observed with increasing amounts of metal ion in the presence of aqueous polyamines buffered at pH = 7.6. Such perturbations manifested as ‘turn-on’ signals from a ratiometric comparison of emission intensities at 390 nm versus 340 nm. Using Pb(II) as the metal mediator, spermine was selectively detected as a 40-fold signal enhancement relative to spermidine, putrescine, cadaverine and several other non-biogenic diamines. Evaluation of additional triamine and tetraamine analytes showed the influence that amine group quantity and spacing had on signal generation. By increasing the ratio of Pb(II) relative to ethynylarene, the detection limit for spermine was successfully lowered to a 25 micromolar level. Noncovalent association between ethynylarene, metal ion and polyamine are believed to promote the observed spectroscopic changes. This study exploits the subtle impact that polyamine structural identity has on transition metal chelation to define a new approach towards polyamine chemosensor development.

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A Gold Nanoparticle‐Based Fluorescence Turn‐On Probe for Highly Sensitive Detection of Polyamines

Cited by 51 publications

References 27 publications

Optical Reading of Contaminants in Aqueous Media Based on Gold Nanoparticles

Optical Reading of Contaminants in Aqueous Media Based on Gold Nanoparticles

Dual‐Mode Optical Sensing of Histamine at Nanomolar Concentrations in Complex Biological Fluids and Living Cells

Spermine detection via metal-mediated ethynylarene ‘turn-on’ fluorescence signaling

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