2022
DOI: 10.1016/j.sjbs.2022.03.028
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A glyphosate-based herbicide disrupted hematopoiesis and induced organ toxicities, ameliorated by vitamin B12 in a mouse model

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Cited by 8 publications
(1 citation statement)
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“…Another study reported that oral administration of 375 mg/kg of GBH for 56 days induced severe anemia, altered platelets and white blood cells, and caused in ammation and oxidative stress in mice. However, supplementation with vitamin B12 attenuated these effects, suggesting a potential role of antioxidants in managing GBH-induced toxicity (Ngatuni et al 2022). Additionally, a study demonstrated that intraperitoneal administration of glyphosate at levels of 25 and 50 mg/kg is clastogenic and cytotoxic to mouse bone marrow, potentially leading to decreased erythrocyte production in the mice (Prasad et al 2009).…”
Section: Discussionmentioning
confidence: 99%
“…Another study reported that oral administration of 375 mg/kg of GBH for 56 days induced severe anemia, altered platelets and white blood cells, and caused in ammation and oxidative stress in mice. However, supplementation with vitamin B12 attenuated these effects, suggesting a potential role of antioxidants in managing GBH-induced toxicity (Ngatuni et al 2022). Additionally, a study demonstrated that intraperitoneal administration of glyphosate at levels of 25 and 50 mg/kg is clastogenic and cytotoxic to mouse bone marrow, potentially leading to decreased erythrocyte production in the mice (Prasad et al 2009).…”
Section: Discussionmentioning
confidence: 99%