A global perspective of lung transplantation: Part 1 - Recipient selection and choice of procedure

Abstract

Lung transplantation has grown considerably in recent years and its availability has spread to an expanding number of countries worldwide. Importantly, survival has also steadily improved, making this an increasingly viable procedure for patients with end-stage lung disease and limited life expectancy. In this first of a series of articles, recipient selection and type of transplant operation are reviewed. Pulmonary fibrotic disorders are now the most indication in the U.S., followed by chronic obstructive pulmonary disease and cystic fibrosis. Transplant centers have liberalized criteria to include older and more critically ill candidates. A careful, systematic, multi-disciplinary selection process is critical in identifying potential barriers that may increase risk and optimize long-term outcomes.

Early postoperative complications after lung transplantation

“…Позднее аналогичная схема внедрена в практику в странах Европы [15]. Введение LAS наряду с либерализацией критериев отбора доноров и реципиентов, широкое использование ex vivo перфузии привело к росту количества трансплантаций в мире и развитию программы трансплантации легких в странах Южной Америки, Восточной и Юго-Восточной Азии и Ближнего Востока [16]. Важной предпосылкой к формированию техники трансплантации легких в нашей стране является создание в 70-х гг.…”

Ex Vivo Lung Perfusion: Current Achievements and Future Directions

“…1 Lung transplant offers the potential for increased quality of life and lifespan for individuals with end-stage lung disease. Although lung transplant volume has increased worldwide, 2 the demand for lung transplant donors exceeds supply 3,4 with up to one-third of potential transplant candidates dying on the waiting list. 5 This disparity relates to concerns for the quality of organs and the narrow window of time between organ procurement and transplant.…”