A Global, Evidence-Based Consensus on the Definition of Gastroesophageal Reflux Disease in the Pediatric Population

Sherman, Philip M.; Hassall, Eric; Fagundes-Neto, Ulysses; Gold, Benjamin D.; Kato, Seiichi; Koletzko, Sibylle; Orenstein, Susan R.; Rudolph, Colin D.; Vakil, Nimish; Vandenplas, Yvan

doi:10.1038/ajg.2009.129

Cited by 391 publications

(406 citation statements)

References 140 publications

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“…Срыгивание представляет собой ретроградный пас-саж (заброс) содержимого желудка в глотку/ротовую полость или из ротовой полости [23]. У младенцев, нахо-дящихся на лактотрофном питании, срыгивание носит физиологический характер и связано с механизмом сосания, когда в желудок попадает избыток воздуха.…”

Section: этиопатогенез функциональных заболеваний у детей раннего возunclassified

Current Issues of Diagnosis and Treatment of Functional Gastrointestinal Disorders in Children

Броева¹,

Сурков²,

Chernikov³

2017

Pediatr. farmakol.

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Section: этиопатогенез функциональных заболеваний у детей раннего возunclassified

Current Issues of Diagnosis and Treatment of Functional Gastrointestinal Disorders in Children

Броева¹,

Сурков²,

Chernikov³

2017

Pediatr. farmakol.

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“…Klinička slika ovisi o dobi djeteta pa su u dojenčadi češća bljuckanja, povraćanja, odbijanje obroka, neutješan plač, zagrcavanja i apneje u spavanju. Kod starije djece javljaju se bolovi u trbuhu, disfagija i odinofagija [2][3][4] . Od ekstraezofagealnih simptoma česti su kronični kašalj, kronični laringitis, astma, faringitis, bol u prsima, bolesti zuba, sinusitis, upala uha i Sandiferov sindrom 2 .…”

Section: Uvodunclassified

Habit cough – cause or consequence of gastroesophageal reflux disease?

Adžamić¹,

Dekanić

Kosec

et al. 2016

Med. flum.

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Sažetak. Cilj: prikaz 15-godišnjeg pacijenta upućenog u našu Kliniku radi kroničnog kašlja i ezofagitisa. Prikaz slučaja: petnaestogodišnji mladić patio je od dugotrajnog kašlja uz koji su se javljale i poteškoće gutanja. Dijagnostičkom obradom postavljena je dijagnoza gastroezofagealne refluksne bolesti (engl. gastroesophageal reflux disease, GERD) i patohistološki dokazanog ezofagitisa koji se na provedeno liječenje značajno smanjuju, ali kašalj ostaje nepromijenjen. Pulmološkom i psihijatrijskom obradom postavljena je dijagnoza psihogenog kašlja te je započeto psihoterapijsko liječenje, nakon čega dolazi do smanjenja mladićevih tegoba. Zaključak: GERD se prezentira širokim spektrom ezofagealnih i ekstraezofagealnih simptoma, od kojih je značajan i kronični kašalj, no kašalj druge etiologije poput psihogenog kašlja može biti i uzrok GERD-u, što diferencijalnodijagnostički moramo razmotriti kod pacijenata u kojih medikamentozna terapija nije dovela do poboljšanja.Ključne riječi: ezofagitis; GERD; psihogeni kašalj; psihoterapija Abstract. Aim: To present a 15-year-old patient admitted to our Clinic because of chronic cough and esophagitis. Case report: A 15-year-old boy suffered from chronic cough along with swallowing difficulties. Diagnostic workup was performed and a diagnosis of gastroesophageal reflux disease (GERD) with pathohistologically proven esophagitis was made with significant improvement after completion of therapy, but cough remained unchanged. The boy was examined by a pulmologist and psychiatrist and they made a diagnosis of habitual cough; psychotherapy was started and resulted in improvement of symptoms. Conclusion: GERD presents with a broad spectrum of esophageal and extraeosphageal symptoms with chronic cough as an important one. Nevertheless, a cough from different origin, such as habitual cough, may cause GERD which must be included in differential diagnosis of patients to whom pharmacological treatment failed to help.

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“…According to current guidelines [11,39,40], no single test is sufficient to make a reliable diagnosis of GERD, as it is often a result of combined clinical assessment and diagnostic tests. Nonetheless, due to the multifaceted clinical presentation and the frequent occurrence of episodic regurgitation in otherwise healthy children, discriminating what is "physiologic" gastro-esophageal reflux (GER) from what is "pathological" gastro-esophageal reflux disease (GERD) can be challenging, particularly in infants.…”

Section: Current Diagnostics Guidelinesmentioning

confidence: 99%

Gastroesophageal Reflux in Children

2017

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Gastro-esophageal reflux (GER) is common in infants and children and has a varied clinical presentation: from infants with innocent regurgitation to infants and children with severe esophageal and extra-esophageal complications that define pathological gastro-esophageal reflux disease (GERD). Although the pathophysiology is similar to that of adults, symptoms of GERD in infants and children are often distinct from classic ones such as heartburn. The passage of gastric contents into the esophagus is a normal phenomenon occurring many times a day both in adults and children, but, in infants, several factors contribute to exacerbate this phenomenon, including a liquid milk-based diet, recumbent position and both structural and functional immaturity of the gastro-esophageal junction. This article focuses on the presentation, diagnosis and treatment of GERD that occurs in infants and children, based on available and current guidelines.

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A Global, Evidence-Based Consensus on the Definition of Gastroesophageal Reflux Disease in the Pediatric Population

Abstract: The consensus statements that comprise the Definition of GERD in the Pediatric Population were developed through a rigorous process. These statements are intended to be used for the development of future clinical practice guidelines and as a basis for clinical trials.

Cited by 391 publications

References 140 publications

Current Issues of Diagnosis and Treatment of Functional Gastrointestinal Disorders in Children

Current Issues of Diagnosis and Treatment of Functional Gastrointestinal Disorders in Children

Habit cough – cause or consequence of gastroesophageal reflux disease?

Gastroesophageal Reflux in Children

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