A Giant Polypoid Gastric Heterotopia of the Ileum as a Cause of Intussusception in an Adolescent

Abstract

No abstract available.

Severe FVII deficiency presenting with Heterotopic gastric mucosa: Hoofbeats may be a zebra

“…The origin of HGM's is usually considered to be a lesion which originates from the primitive gut epithelium as a congenital anomaly which dissociates from the primordial stomach at the fourth week of gestation and undergoes hyperplasia over time. 12 HGM can present as mild dyspepsia, GI bleeding or intestinal obstruction, [4][5][6][7][8][9]13,14 and is best diagnosed by capsule endoscopy if in the small bowel, as upper and lower endoscopy is limited to duodenum and colon; imaging including ultrasound, CT or MRI is not sensitive for polypoid masses, and tagged scans accurately localize GI bleeding sites is only˜52% of cases. 15 Observation is recommended unless there is bleeding or other complications such as intestinal obstruction.…”

“…Our patient was diagnosed by the second capsule endoscopy as documentation of small bowel pathology with capsule endoscopy is ˜45-76%. 13 There have been a handful of published case reports of pediatric patients with lower gastrointestinal bleeding due to gastric heterotopia of the small intestine [4][5][6][7][8][9]13,14 but as yet, none of these cases have included a pediatric patient with an underlying bleeding disorder, thus making this case of particular interest. This clinical scenario emphasizes the need for a collaborative and diligent evaluation by the multispecialty team to identify the root cause for persistent GI bleeding which could be obscured by other explanations.…”

“…HGM is a rare lesion with unknown prevalence which is in the differential diagnosis of lower GI tract bleeding. [4][5][6][7][8][9] Here we present the pathway to diagnosis and the management of a young male with severe FVII deficiency followed for a decade for anemia and GI bleeding who was ultimately found to have a rare small intestinal lesion, HGM, as an explanation for his symptoms. This case represents the first documented report of a severe FVII deficient individual presenting with a rare small bowel lesion, masquerading as non-responsive GI bleeding.…”

Severe FVII deficiency presenting with heterotopic gastric mucosa: hoofbeats may be a zebra

“…The origin of HGM's is usually considered to be a lesion which originates from the primitive gut epithelium as a congenital anomaly which dissociates from the primordial stomach at the 4th week of gestation and undergoes hyperplasia over time. 13 HGM can present as mild dyspepsia, GI bleeding or intestinal obstruction, [4][5][6][7][8][9]14,15 and is best diagnosed by capsule endoscopy if in the small bowel, as upper and lower endoscopy is limited to duodenum and colon; imaging including ultrasound, computed tomography or magnetic resonance imaging is not sensitive for polypoid masses, and tagged scans accurately localise GI bleeding sites is only∼52% of cases. 16 Our patient was diagnosed by the second capsule endoscopy as documentation of small bowel pathology with capsule endoscopy is ∼45%-76%.…”

“…Heterotopic gastric mucosa (HGM) is a rare lesion with unknown prevalence which is in the differential diagnosis of lower GI tract bleeding. [4][5][6][7][8][9] Here we present the pathway to diagnosis and the management of a young male with severe FVII deficiency followed for a decade for anemia and GI bleeding who was ultimately found to have a rare small intestinal lesion, HGM, as an explanation for his symptoms. This case represents the first documented report of a severe FVII deficient individual presenting with a rare small bowel lesion, masquerading as non-responsive GI bleeding.…”