A Giant Gastrointestinal Stromal Tumor of Duodenal Origin with Spontaneous Rupture Bleeding: A Case Report

Abstract

BackgroundThe duodenum is a rare site of gastrointestinal stromal tumors (GISTs). The unique anatomical characteristics and rich blood supply of the duodenum make it difficult to treat duodenal GISTs in patients with bleeding.Case presentationHere we report a case of a 76-year-old female was hospitalized with a large GIST that originated in the duodenum. Imaging assessment suggested that the tumor could not be radically resected. However, the tumor was rupturing and bleeding, and therefore pancreaticoduodenectomy had to be performed. After receiving imatinib postoperatively, the patient has recovered during the 1 year after the operation.ConclusionThe results of this case suggest that pancreaticoduodenectomy may be a better choice for duodenal GISTs with rupture and bleeding.