A Geometric Optimization Approach for the Detection and Segmentation of Multiple Aneurysms

Abstract

We present a method for detecting and segmenting aneurysms in blood vessels that facilitates the assessment of risks associated with the aneurysms. The detection and analysis of aneurysms is important for medical diagnosis as aneurysms bear the risk of rupture with fatal consequences for the patient. For risk assessment and treatment planning, morphological descriptors, such as the height and width of the aneurysm, are used. Our system enables the fast detection, segmentation and analysis of single and multiple aneurysms. The method proceeds in two stages plus an optional third stage in which the user interacts with the system. First, a set of aneurysm candidate regions is created by segmenting regions of the vessels. Second, the aneurysms are detected by a classification of the candidates. The third stage allows users to adjust and correct the result of the previous stages using a brushing interface. When the segmentation of the aneurysm is complete, the corresponding ostium curves and morphological descriptors are computed and a report including the results of the analysis and renderings of the aneurysms is generated. The novelty of our approach lies in combining an analytic characterization of aneurysms and vessels to generate a list of candidate regions with a classifier trained on data to identify the aneurysms in the candidate list. The candidate generation is modeled as a global combinatorial optimization problem that is based on a local geometric characterization of aneurysms and vessels and can be efficiently solved using a graph cut algorithm. For the aneurysm classification scheme, we identified four suitable features and modeled appropriate training data. An important aspect of our approach is that the resulting system is fast enough to allow for user interaction with the global optimization by specifying additional constraints via a brushing interface.

Vascular surface segmentation for intracranial aneurysm isolation and quantification

“…As shown on Figure 4 the segmentation and isolation with cutting plane does not seem robust enough to isolate aneurysm from the vessels regardless of the position and the shape of aneurysm. Though prior work on isolation with non-planar separation curves showed some promising results [20,16], none of them achieved clinically acceptable results and robust enough performance. Small aneurysms with curved veins proved to be extremely challenging.…”

“…The second drawback is that the user has to click on the aneurysm to initialize the method's parameters. Lawonn et al [16] proposed a geometric optimization approach for the detection and segmentation of multiple aneurysms in two stages. First, a set of aneurysm candidate regions was identified by segmenting regions of the vessels.…”

Vessel Maps: A Survey of Map‐Like Visualizations of the Cardiovascular System

“…Extracted surfaces can also be further processed and given additional information, such as relevant landmarks or morphological features. For example, aneurysms can be detected and segmented in models of vessel trees [LMW * 19].…”

Robust Mesh Segmentation Using Feature-Aware Region Fusion

“…Xu et al [ 36 ] aimed to cut out each tooth in a 3D dental model. Lawonn et al [ 37 ] performed segmentation on the 3D surfaces of vessels and then identified aneurysms. As an extension, the segmentation of point clouds has drawn a lot of attention.…”