A genetic study of two French Guiana Amerindian populations

Tchen, Paul; Bois, E; Seger, J; Grenand, Pierre; Feingold, Josué

doi:10.1007/bf00278728

Cited by 18 publications

(9 citation statements)

References 35 publications

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“…The variability observed in the third component of complement was unex pected, since in four other tribes (Cuiva, Emerillon, Oiampi and Shuara) only C3S has been found [Goeddeet al, 1977;Tchen et al, 1978Tchen et al, , 1979. Since all of them live in northern South America (Ecuador, Vene zuela and French Guiana), this finding may reflect heterogeneity between nor thern and southern Indian populations.…”

Section: Resultsmentioning

confidence: 89%

HLA Antigens and Other Genetic Markers in the Mapuche Indians of Argentina

Haas¹,

Salzano

Araujo³

et al. 1985

Hum Hered

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A total of 107 Mapuche Indians living in western Argentina were studied with respect to 16 genetic systems. For HLA, there were a few differences in relation to previous studies; and considering the averages observed in 15 other South American tribes, Mapuche Indians showed low values for A2, A9 and C3, but high ones for A28 and B16. This is the first report of the presence (in low frequencies, 1–6%) of alleles C2, C6 and C7, as well as of DR antigens (most frequent alleles DR4 and DR2) in South American Indians. Some peculiar reactions shown by products of locus B suggest the presence of antigens that are characteristic of the Mapuche. As for the other systems, the frequencies of R¹ (Rh) and PGM¹₁ were lower but those for r (Rh), GLO¹ and Hp¹ were higher than the averages obtained considering previous studies of this ethnic group. Other salient findings were the variability observed in the PGM2 and C3 systems, and the low prevalence of Bf^S.

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Section: Resultsmentioning

confidence: 89%

HLA Antigens and Other Genetic Markers in the Mapuche Indians of Argentina

Haas¹,

Salzano

Araujo³

et al. 1985

Hum Hered

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“…The Gm and Km allotypes were determined by the classical hemagglutination inhibition method, with human antisera (Field and Dugoujon, 1989). The transferrin, Rhesus ''d,'' PGM2, and G2M*23 markers were excluded from the statistical analysis due to their monomorphism in South American Indians (Tchen et al, 1978a(Tchen et al, ,b, 1981Salzano et al, 1988). The ABO and Kell systems, which are also monomorphic in South American Indians, were included to evaluate admixture.…”

Section: Methodsmentioning

confidence: 99%

“…Primary data concerning the French Guiana Indians have been collected as early as the 1960s (Larrouy et al, 1964a,b;Bois and Feingold, 1972;Daveau et al, 1975;Tchen et al, 1978aTchen et al, ,b, 1981Dugoujon et al, 1994aDugoujon et al, ,b, 1995; nevertheless, they have been unequally examined as compared with other South American Indian populations. Indeed, no relevant DNA studies are available for these populations.…”

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confidence: 99%

Genetic studies in French Guiana populations: Synthesis

Mazières

Sevin

Bonnet

et al. 2006

American J Phys Anthropol

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Twelve blood group and protein systems from a total of 819 individuals from six tribal groups (Apalaí-Wayana, Emerillon, Kaliña, Palikur Wayampi, and Wayana) living in French Guiana and Brazil were compared with each other and integrated with previous results from 17 other South Amerindian populations studied for the same genetic markers. Using correspondence analysis, map methodologies, and maximum linkage cluster analysis developed with the UPGMA method, we attempted to establish the genetic position of these tribes among South American Indians. Peripheral positions for the Emerillon and the Palikur were observed. Ethnohistorical data in French Guiana suggest that a strong founder effect for the former and endogamy for the latter could have generated the genetic differentiation of these two ethnic groups. However, when considered in a wider context, all French Guiana Natives cluster together in an intermediate position as compared with 17 other Amerindian groups studied for the comparison.

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“…The number of non-Indian subjects tested in South America (23,839) is about 40% higher than the total number of Indians (Table 2). There are now 13 variants that (1994); Krahó, 193, Neel (1978); Macushi, 694, Neel et al (1977), Salzano et al (1984); Mundurucu, 361, Salzano et al (1991), Santos et al (1998); Noanama, 155, Kirk et al (1974); Pacaá s Novos, 222, Salzano et al (1985b); Palikour, 115, Santos et al (1998); Parakanã , 252, Black et al (1980Black et al ( , 1988; Quechua, 39, Modiano et al (1972); Sateré-Mawé, 170, Salzano et al (1985a);Surui, 198, Callegari-Jacques et al (1994), Salzano et al (1998); Tenharim, 20, Santos et al (1998);Ticuna, 761, Neel et al (1980); Urubu-Kaapor, 205, Black et al (1988); Waiã pi, 361, Tchen et al (1978), Black et al (1983); Wai Wai, 166, Callegari-Jacques et al (1996); Zoró, 76, Salzano et al (1998 Tables 1 and 2 is more meaningful when considered in the context of the information provided in Tables 3 and 4. The provisional assignment of Belém 2 to albumin México by direct electrophoretic comparisons in four buffer systems is rendered plausible by previous studies in which the structural studies confirmed the electrophoretic findings (see Arai et al, 1989), as well as by the present results concerning albumin Fortaleza.…”

Section: Resultsmentioning

confidence: 99%

Albumin genetic variability in South America: Population distribution and molecular studies

et al. 1999

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A total of 5,020 individuals living in two southern Brazilian states were screened in relation to albumin types; two variants were found, in Passo Fundo (Nagasaki 2) and Vera Cruz (Tradate 2). Another variant, detected in the northeast, was identified as Porto Alegre 2, which also occurs in other places in Brazil, as well as in India, Pakistan, and Turkey. The results were integrated with those obtained in other studies in South America, yielding a total of 16,941 Amerindians and 23,839 non-Indian subjects. Molecular and physiological studies performed in some of the variants suggested clues to explain the restricted distribution of albumin Yanomama 2 and the widespread occurrence of albumin Maku. Am. J. Hum. Biol. 11: 359-366, 1999. © 1999 Human serum albumin, the most abundant protein in blood plasma, is physiologically important due to its unique ability of reversibly binding an extensive series of endogenous and exogenous compounds. Structurally, it is a nonglycoprotein composed of a single polypeptide chain subdivided in three homologous domains, which total 585 amino acids. To date, more than 50 genetic variants of albumin have been characterized at the protein and/or DNA level. The molecular distribution of these changes is clearly nonrandom, with clusters at the propeptide, N-terminus, and C-terminal regions of subdomains II B and III B. Moreover, population prevalences of these variants also present several interesting features. They are rare in most ethnic groups, but show some polymorphic variants especially in Amerindians (see Madison et al., 1994;Nielsen et al., 1997).The present report presents: a) a detailed review of the population distribution of albumin variants in South America, including new data in 5,020 individuals; b) a description of the molecular changes in three Brazilian variants; and c) a review of the physiological studies performed in four of these types, trying to integrate all of the results in a unified manner.

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A genetic study of two French Guiana Amerindian populations

Cited by 18 publications

References 35 publications

HLA Antigens and Other Genetic Markers in the Mapuche Indians of Argentina

HLA Antigens and Other Genetic Markers in the Mapuche Indians of Argentina

Genetic studies in French Guiana populations: Synthesis

Albumin genetic variability in South America: Population distribution and molecular studies

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