“…Conversely, early expression of an activated form of tai ( taiΔB ) can cause abnormally early movements of the border cell cluster, but only in combination with ectopically early specification via STAT activation (Jang et al, 2009). Several key ecdysone targets have been identified during metamorphosis (Beckstead et al, 2005; Beckstead et al, 2007), and in ovary (Ables et al, 2015; Ables and Drummond-Barbosa, 2010; Ables et al, 2016; Buszczak et al, 1999; Terashima and Bownes, 2005), but few are known to have roles in cell motility. Furthermore, it is not clear how downstream targets for EcR, Tai, STAT, and Slbo coordinate their activities to result in proper temporal control of border cell movements.…”