Solubilities of acetylene in pure solvents, hexane, cyclohexane, hexadecane, benzene, carbon disulfide, carbon tetrachloride, methanol, butanol and ethylene glycol, and mixtures, hexane‐hexadecane and butanol‐ethylene glycol, are reported at atmospheric pressure and temperatures ranging from 0 C to 50 C. Hydrogen bonding (H‐bonding) factors expressed by a simplified Margules equation were found useful to correlate the solubilities of gases in the pure solvents as well as the solvent mixtures.