A general neuropsychological model of delusion

Braun, Claude M. J.; Suffren, Sabrina

doi:10.1080/13546800903442314

Cited by 32 publications

(24 citation statements)

References 156 publications

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“…This breakdown in function and connectivity could be linked to the AD brain pathology. Furthermore, in a general neuropsychological model of delusion, Braun and Suffren (2011) have pointed to the importance of the left hemisphere overactivity secondary to the right hemisphere impairment in the DSM-IV delusional disorder. As the left hemisphere is an activator and the right hemisphere an inhibitor of mentation and behavior, the two hemispheres compete and cooperate to maintain balance.…”

Section: Discussionmentioning

confidence: 98%

Psychosis associated behavioral and psychological signs and symptoms in mild cognitive impairment and Alzheimer's dementia

Mussele

Mariën

Saerens

et al. 2014

Aging & Mental Health

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Section: Discussionmentioning

confidence: 98%

Psychosis associated behavioral and psychological signs and symptoms in mild cognitive impairment and Alzheimer's dementia

Mussele

Mariën

Saerens

et al. 2014

Aging & Mental Health

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“…On one hand, the left hemisphere is considered as an interpreter, tending to reduce uncertainty by creating explanations, filling gaps of information, and making inference (Braun and Suffren, 2011). On the other hand, the right hemisphere is considered as a realist, striving to reduce inconsistencies between hypotheses and reality by detecting conflicts, updating information, supporting mental set shifting (Goel et al, 2013), and monitoring and inhibiting thoughts and behavior (Chatham et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Hemispheric Differences in White Matter Microstructure between Two Profiles of Children with High Intelligence Quotient vs. Controls: A Tract-Based Spatial Statistics Study

et al. 2017

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Objectives: The main goal of this study was to investigate and compare the neural substrate of two children's profiles of high intelligence quotient (HIQ).Methods: Two groups of HIQ children were included with either a homogeneous (Hom-HIQ: n = 20) or a heterogeneous IQ profile (Het-HIQ: n = 24) as defined by a significant difference between verbal comprehension index and perceptual reasoning index. Diffusion tensor imaging was used to assess white matter (WM) microstructure while tract-based spatial statistics (TBSS) analysis was performed to detect and localize WM regional differences in fractional anisotropy (FA), mean diffusivity, axial (AD), and radial diffusivities. Quantitative measurements were performed on 48 regions and 21 fiber-bundles of WM.Results: Hom-HIQ children presented higher FA than Het-HIQ children in widespread WM regions including central structures, and associative intra-hemispheric WM fasciculi. AD was also greater in numerous WM regions of Total-HIQ, Hom-HIQ, and Het-HIQ groups when compared to the Control group. Hom-HIQ and Het-HIQ groups also differed by their hemispheric lateralization in AD differences compared to Controls. Het-HIQ and Hom-HIQ groups showed a lateralization ratio (left/right) of 1.38 and 0.78, respectively.Conclusions: These findings suggest that both inter- and intra-hemispheric WM integrity are enhanced in HIQ children and that neural substrate differs between Hom-HIQ and Het-HIQ. The left hemispheric lateralization of Het-HIQ children is concordant with their higher verbal index while the relative right hemispheric lateralization of Hom-HIQ children is concordant with their global brain processing and adaptation capacities as evidenced by their homogeneous IQ.

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“…Finally, the formation of additional cognitive contents, especially of the higher order, cannot be easily correlated with brain damage. The last argument is mainly supported by case analysis of delusions induced by psychoactive substances or the occurrence of delusions associated with hypermetabolism or hyperperfusion of certain parts of the brain [14,15].…”

Section: Model Of the Left Hemisphere Releasementioning

confidence: 93%

“…The authors, C. Braun and S. Suffren [14] gathered factors which determined the need to enrich the two-factor model. Firstly, the majority of diagnosed delusions are not of monothematic nature.…”

Section: Model Of the Left Hemisphere Releasementioning

confidence: 99%

Usefulness of models in the process of qualifying contents as delusional – case analysis

Janík¹,

Biegańska²

2015

Arch Psych Psych

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SummaryAim: The purpose of this study was to attempt to apply a two-factor diagnostic model for delusional content qualification. Method: This is a case study of a patient with a history of ischaemic stroke who developed delusional beliefs. Results:The two-factor diagnostic model has shown promising applicability in the case analysed, however, guidance is provided on the need to expand and change some of the criteria with the possibility of complementing the model with elements from neurobiological models. Conclusions:The case analysis allowed us to point out the strengths and weaknesses of the diagnostic model discussed. We propose that strictly neurobiological diagnostic categories should be replaced by those that allow the diagnosis of cognitive deficits. We also hypothesise that problems with inference, as one of the main factors contributing to delusions, should not be analysed only in terms of the damage to the right hemisphere. delusions / delusional models / diagnostic clues / case studyThis article analyses the usefulness of several models of delusions described in the literature in the diagnostic process of a patient with a history of ischaemic stroke affecting the right hemisphere. Previous studies hypothesised on the process of delusional content formation and verified the delusional contents using available diagnostic procedures. Creating models to explain how certain disorders develop has two main advantages: it shows how a specific disorder forms and indicates the main types of factors involved in this process. Thus, it enables a better understanding of the essence of the disorder and helps formulate diagnostic guidelines.Models of this type can have various forms: from a simple presentation of a causal relationship between a factor and a disorder to complex, multifactorial network models, in which each element can potentially interact with the other. The task of theoretical models of delusions will be to indicate the main factors necessary for the emergence of delusional beliefs and to describe the dynamics of the process leading from these factors to delusion formation. The need to create such models primarily stems from a strong internal differentiation within the category of beliefs determined as delusions. Due to this heterogeneity, it is diagnostically interesting to identify and differentiate such factors depending on the contents of delusions.

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A general neuropsychological model of delusion

Cited by 32 publications

References 156 publications

Psychosis associated behavioral and psychological signs and symptoms in mild cognitive impairment and Alzheimer's dementia

Psychosis associated behavioral and psychological signs and symptoms in mild cognitive impairment and Alzheimer's dementia

Hemispheric Differences in White Matter Microstructure between Two Profiles of Children with High Intelligence Quotient vs. Controls: A Tract-Based Spatial Statistics Study

Usefulness of models in the process of qualifying contents as delusional – case analysis

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