“…These effects are usually coupled in the postprocessing phase, making the alignment task even more demanding. Conventional methods, like center of mass (CoM), 47 cross-correlation, 48 , 49 and iterative techniques, 50 , 51 , 52 , 53 , 54 are often applied for tomography stack optimization, but all have their limitations, mostly on accuracy and efficiency. Correcting coupled or mixed types of motion inaccuracy, drift, and vibration in a faster and more accurate fashion is demanding, and extensive research is being undertaken on DL image alignment in the STDPP.…”