A General and Facile Synthesis of Novel Polysubstituted Quinazolin‐4(3H)‐ones

Abstract

A simple and efficient approach to synthesize novel polysubstituted quinazolin-4 (3H)-ones has been developed, and the key step is a sequential procedure involved iron-mediated reduction and acid-catalytic cyclization. The present method provides a convenient and practical strategy for the synthesis of quinazolin-4(3H)-one derivatives.